AI Article Synopsis

  • Linezolid therapy has been linked to a rare side effect known as black hairy tongue (BHT), with very few documented cases in current medical literature.
  • A case report details a 28-year-old woman who developed BHT after taking linezolid for 5 days, but she recovered quickly after stopping the medication and maintaining good oral hygiene.
  • The article emphasizes the importance of recognizing this unusual side effect to help healthcare providers diagnose and manage it effectively, and it includes a review of past cases to enhance understanding.

Article Abstract

Unlabelled: Linezolid-induced black hairy tongue (BHT) is a highly scarce adverse event of linezolid therapy. To date, there are very few reported cases in contemporary literature. The onset and mechanism of BHT are also not well understood.

Case Report: In this article, the authors report a case of BHT in a 28-year-old female following 5 days of therapy with linezolid. The patient recovered well within few days of discontinuation of the drug and maintaining oral hygeine. Patient reassurance and counselling was integral to the management.

Discussion And Conclusion: This case report and review depict a rare adverse effect of linezolid and discuss its clinical implications aiding healthcare professionals in an early diagnosis and cromulent management strategy. The authors also present a compilation of previously reported literature on linezolid-induced BHT to support the discussion.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289492PMC
http://dx.doi.org/10.1097/MS9.0000000000000834DOI Listing

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Article Synopsis
  • Linezolid therapy has been linked to a rare side effect known as black hairy tongue (BHT), with very few documented cases in current medical literature.
  • A case report details a 28-year-old woman who developed BHT after taking linezolid for 5 days, but she recovered quickly after stopping the medication and maintaining good oral hygiene.
  • The article emphasizes the importance of recognizing this unusual side effect to help healthcare providers diagnose and manage it effectively, and it includes a review of past cases to enhance understanding.
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Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series.

Infect Drug Resist

September 2022

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.

Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these patients.

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