Unlabelled: Glioblastoma is the most common primary malignant brain tumor in adults. It is enhanced by the abnormal proliferation of central nervous system cells called astrocytes. Microvascular endothelial proliferation is one of the criteria for a histological diagnosis. Hypervascular glioblastoma simulating an arteriovenous malformation is an involuntary manifestation and constitutes a rare entity.
Case Presentation: The authors report a case of a 44-year-old patient with no history followed. Symptoms began 6 months ago with the gradual onset of headaches without vomiting or seizures associated with a drop in normal visual acuity without neurological deficit. Cerebral imaging including cerebral angiography concluding with a right parieto-occipital cerebral process probably associated with an arteriovenous malformation.
Clinical Discussion: The management was surgical by biopsy after a right parieto-occipital bone flap concluding in glioblastoma. The patient needs chemotherapy and radiotherapy sessions with good clinical evolution.
Conclusion: The coexistence of an arteriovenous malformation and glioblastoma remains an association whose pathophysiology still remains to be explored.
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http://dx.doi.org/10.1097/MS9.0000000000000593 | DOI Listing |
BMJ Case Rep
January 2025
Neonatology, Bharati Vidyapeeth (Deemed to be University) Medical College, Pune, Maharashtra, India
Arteriovenous malformations (AVMs) are rare congenital vascular malformations with associated morbidities. We describe a neonatal case of upper limb high-flow AVM presenting with upper limb soft tissue mass and postnatal high-output heart failure. Doppler study suggested high-flow AVM, and later magnetic resonance angiography of the right upper limb confirmed the diagnosis.
View Article and Find Full Text PDFJ Clin Neurosci
January 2025
Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, United States. Electronic address:
Introduction: Cerebral arteriovenous malformations (AVMs) represent a complex neurosurgical challenge with management strategies that vary significantly across regions. The decision to treat unruptured AVMs, in particular, is controversial, with options ranging from conservative management to surgical excision or endovascular embolization. This study investigates regional variations in treating unruptured and ruptured AVMs in the United States.
View Article and Find Full Text PDFPulm Circ
January 2025
National Heart and Lung Institute, Imperial College London UK.
Pulmonary arteriovenous malformations (PAVMs) cause cerebral abscess and ischemic stroke due to paradoxical emboli, risks that are increasingly recognized. We report the evolving placement of thoracic surgery in multi-disciplinary team management of PAVMs that were sporadic or associated with hereditary hemorrhagic telangiectasia. From 1983 to 2006, all patients receiving elective treatment had embolization.
View Article and Find Full Text PDFSurg Neurol Int
December 2024
Department of Surgery, Section of Neurosurgery, Aga Khan University, Karachi, Pakistan.
Background: Intracranial arteriovenous malformations (AVMs) are extremely rare in the pediatric population, with an estimated prevalence of 0.014-0.028%.
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