Unlabelled: Sarcoidosis is an idiopathic, multisystemic granulomatous disorder involving the eye with various ocular presentations, the most common being sarcoid uveitis. The diagnosis was based on typical clinical features, chest radiography, laboratory findings and biopsy based on revised International Workshop on Ocular Sarcoidosis criteria. Here in, the authors aim to present the first report on the trend of cases of sarcoid uveitis in Nepal.
Materials And Methods: A retrospective quantitative cross-sectional study was conducted at the uveitis clinic of the Institute of Medicine by obtaining medical data from the medical record section on sarcoid uveitis cases visiting from March 2018 to March 2021. Demographic profile, ocular findings, laboratory findings and treatment details were documented and statistical analysis was done via Statistical Program for Social Science (SPSS) version 23.
Results: Out of 50 eyes of 30 patients included in the study; 66.6% patients (=20) had bilateral and 33.3% (=10) had unilateral ocular involvement. Anterior with intermediate uveitis (26.7%) was the most common type of uveitis among the cases. Serum angiotensin converting enzyme was raised in 66.7%, Chest X-ray showed hilar changes in 63.33%, and high-resolution computed tomography showed mediastinal, hilar lymphadenopathy with or without the involvement of the lung in 63.33% of patients.
Conclusion: Sarcoid uveitis may have varied ocular presentations, the commonest being anterior and intermediate uveitis. The commonest complications are cataract and cystoid macular oedema, which are associated with vision loss. Steroids and immunomodulators are the mainstays of treatment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289532 | PMC |
| http://dx.doi.org/10.1097/MS9.0000000000000853 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tattoo-associated Uveitis in Sarcoidosis.
Ophthalmol Retina
December 2024
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas.
Successful surgical management of uveitic glaucoma in a sarcoidosis patient with cutaneous manifestations.
BMJ Case Rep
December 2024
Ophthalmology, Western Eye Hospital, Imperial College Healthcare NHS Trust, London, UK.
Sarcoidosis is a systemic granulomatous disease with variable ocular involvement. The most common ocular manifestation is uveitis, which can have potentially sight threatening complications such as glaucoma. We present the case of a man in his 30s with sarcoidosis and recurrent anterior uveitis, necessitating surgical intervention to control intraocular pressure and prevent further glaucomatous optic neuropathy progression.
View Article and Find Full Text PDFPatterns and Outcomes of Pediatric Uveitis in a University-Based Tertiary Referral Center in Riyadh, Saudi Arabia.
Ocul Immunol Inflamm
December 2024
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Article Synopsis
- The study aimed to analyze the patterns and outcomes of uveitis in children through a retrospective patient review.
- A total of 184 pediatric patients were examined, revealing that panuveitis was the most common type, with a significant number displaying non-granulomatous and non-infectious uveitis.
- After one year, most patients (85.4%) had improved vision, achieving at least 20/40 visual acuity, and Vogt-Koyanagi-Harada disease was identified as the most prevalent specific diagnosis.
Prevalence and Incidence of Uveitis in Korean Patients with Sarcoidosis: A Population-Based Study.
Ocul Immunol Inflamm
November 2024
Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Article Synopsis
- Sarcoidosis is an inflammatory disease with various symptoms, and this study focuses on the incidence and prevalence of sarcoidosis-related uveitis, particularly in South Korea, to gather important epidemiological insights.
- Utilizing a nationwide health database from 2010 to 2019, the research analyzed cases of sarcoidosis and uveitis, examining incidence rates, gender differences, age of diagnosis, treatment patterns, and recurrence types among the patients.
- The findings revealed that 28.8% of sarcoidosis patients experienced uveitis, mostly recurrent, with anterior uveitis being the most common; the study underscores the necessity for regular eye examinations and tailored treatments for sarcoidosis patients in Korea due to the high
Clinico-pathologic correlation in ocular sarcoidosis.
Am J Ophthalmol Case Rep
December 2024
Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Purpose: This case describes the unique course and management of a patient with progressive, refractory multi-system sarcoidosis that initially presented with ocular and dermatologic findings.
Observations: A 47-year-old male presented with acute anterior uveitis and was found to have simultaneous inflammation of his skin at a tattoo site. Diagnosis of ocular sarcoidosis was confirmed through skin biopsy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!