A brown recluse spider (BRS) bite is challenging to confirm, but can be clinically diagnosed by considering the location, the season of the year and the clinical manifestations. We described a 26-year-old male who presented after a BRS bite with a skin lesion, bruising, severe swelling and diffuse blisters on the right lower extremity after 3 days. This case should be considered in the differential diagnosis of necrotizing fasciitis. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, it can have devastating outcomes.
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http://dx.doi.org/10.1093/jscr/rjad357 | DOI Listing |
PLoS One
October 2024
Molecular Ecology Group, Water Research Institute, National Research Council of Italy, Verbania Pallanza, Italy.
Fear of spiders is a widespread condition often disproportionate to the actual danger spiders pose to humans. Likely rooted in evolutionary history, fear of spiders might also have a cultural component. Recent studies have shown that a significant fraction of spider-related media reports are misleading and sensationalistic.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
Department of Cell Biology, Federal University of Paraná (UFPR), Curitiba 81530-900, PR, Brazil. Electronic address:
Spiders of Loxosceles genus, or Brown spiders produce a potent venom with minimal volume and protein content. Among its toxins, phospholipases D (PLDs) are notable for causing primary local and systemic manifestations observed following envenomation. They degrade cellular phospholipids, mainly sphingomyelin and lysophosphatidylcholine.
View Article and Find Full Text PDFCureus
July 2024
Department of Emergency Medicine, Ascension Health, Murfreesboro, USA.
Acta Trop
October 2024
Department of Cell Biology, Federal University of Paraná (UFPR), Curitiba, 81530-900, PR, Brazil. Electronic address:
Loxoscelism is the pathological condition triggered by a brown spider bite. The venom of these spiders is rich in phospholipases D (PLDs), which can induce virtually all local and systemic manifestations. Recombinant mutated PLDs from clinically relevant Loxosceles species in South America have been investigated as potential antigens to develop novel therapeutic strategies for loxoscelism.
View Article and Find Full Text PDFHeliyon
July 2024
Laboratorio de Estructura Biomolecular, Centro de Investigación en Alimentación y Desarrollo, A. C., Hermosillo, Sonora, Mexico.
spp. spiders can cause serious public health issues. Chemical control is commonly used, leading to health and environmental problems.
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