In parallel with the fast growth of the second-hand aviation market, the importance of promoting remanufacturing analytics has increased. However, end-of-life (EoL) aircraft parts remanufacturing operations are still underdeveloped. Disassembly, the most challenging and central activity in remanufacturing, directly affects the EoL product recovery's profitability and sustainability. Disassembly sequence planning (DSP) devises ordered and purposeful parting for all potentially recoverable components before physical separations. However, the complexities and uncertainties of the EoL conditions engender unpredictable DSP decision inputs. The EoL DSP needs emergent evidence of cost-effective solutions in view of Industry 4.0 (I4.0) implications and stakeholders' benefits. Among the I4.0 technologies, X-reality (XR) particularly hits the mainstream as a cognitive and visual tool consisting of virtual reality, augmented reality, and mixed reality. Recently, with the advance of I4.0 phenomenon, lean management has been theorized and tested through complementary collaboration. Since the research of integrating lean and XR into the EoL DSP is underexplored in literature, XR and lean are investigated as assistive enablers in the DSP. This study has a two-fold purpose: (1) identifying the key concepts of DSP, I4.0, XR, and lean, and extending the literature by reviewing the previous efforts of EoL aircraft remanufacturing, XR-assisted DSP, and XR-lean applications; (2) proposing "Smart Disassembly Sequence Planning (SDSP)" as a new EoL decision-support agenda after analyzing relational advantages and evolving adaptability. The barriers and limitations are highlighted from the recent associated topics, concrete academic information for developing digitalized disassembly analytics is provided, and new trends are added for future disassembly research.
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http://dx.doi.org/10.1007/s00170-023-11581-0 | DOI Listing |
Sci Rep
January 2025
School of Mechanical Engineering, Hefei University of Technology, Hefei, 230009, China.
Designing mobile electronic products for easy disassembly is crucial for promoting resource recycling. However, many current approaches overlook the need to consider the disassembly of parts from the perspective of the overall product structure and practical recycling requirements, leading to potentially suboptimal or unnecessary optimization strategies. This study introduces a novel visual disassembly information model called the "Peony Diagram.
View Article and Find Full Text PDFNat Commun
January 2025
Goethe University Frankfurt, Institute for Cardiovascular Physiology, Frankfurt, Germany.
The coordination of chromatin remodeling is essential for DNA accessibility and gene expression control. The highly conserved and ubiquitously expressed SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex plays a central role in cell type- and context-dependent gene expression. Despite the absence of a defined DNA recognition motif, SWI/SNF binds lineage specific enhancers genome-wide where it actively maintains open chromatin state.
View Article and Find Full Text PDFMethods Mol Biol
January 2025
Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.
Hox genes play a pivotal role during development. Their expression is tightly controlled in a spatiotemporal manner, ensuring that specific body structures develop at the correct locations and times during development. Various genomics approaches have been used to capture temporal and dynamic regulation of Hox gene expression at the nucleosome/chromatin level.
View Article and Find Full Text PDFNat Commun
December 2024
State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai, PR China.
The INO80 chromatin remodeling complex plays a critical role in shaping the dynamic chromatin environment. The diverse functions of the evolutionarily conserved INO80 complex have been widely reported. However, the role of INO80 in modulating the histone variant H2A.
View Article and Find Full Text PDFAnal Chem
January 2025
Department of Chemistry, Wuhan University, Wuhan 430072, China.
MicroRNAs (miRNAs) regulate a myriad of biological processes and thus have been regarded as useful biomarkers in biomedical research and clinical diagnosis. The specific and highly sensitive detection of miRNAs is of significant importance. Herein, a sensitive and rapid dual-amplification elemental labeling single-particle inductively coupled plasma-mass spectrometry (spICP-MS) analytical method based on strand displacement amplification (SDA) and CRISPR/Cas12a was developed for miRNA-21 detection.
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