Prediction of the Penetration Radius of Cumulative Blasting.

ACS Omega

College of Safety Science and Engineering, Liaoning Technical University, Liaoning, Fuxin 123000, China.

Published: June 2023

To improve the efficiency of coal seam gas extraction, the influence characteristics of different factors on the penetration effect of cumulative blasting were determined and the hole spacing was effectively predicted; in this work, we used ANSYS/LS-DYNA numerical simulation software to establish the penetration model of cumulative blasting. Combined with an orthogonal design scheme, the crack radius prediction of cumulative blasting was studied. A prediction model for predicting the fracture radius of cumulative blasting based on three groups of different factors was established. The results showed that the primary and secondary order of factors that affected the fracture radius of cumulative blasting was as follows: ground stress > gas pressure > coal firmness coefficient. The penetration effect decreased with increasing ground stress and decreased with an increase in the gas pressure and coal firmness coefficient. The industrial field test was carried out. The gas extraction concentration increased by 73.4% after cumulative blasting, and the effective crack radius of cumulative blasting was approximately 5.5-6 m. The maximum error of the numerical simulation was 1.2%, and the maximum error of the industrial field test was 6.22%, which proved that the crack radius prediction model of cumulative blasting was correct.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286281PMC
http://dx.doi.org/10.1021/acsomega.3c02453DOI Listing

Publication Analysis

Top Keywords

cumulative blasting
36
radius cumulative
16
crack radius
12
cumulative
9
blasting
9
gas extraction
8
numerical simulation
8
model cumulative
8
radius prediction
8
prediction model
8

Similar Publications

Military breachers are routinely exposed to repetitive low-level blast overpressure, placing them at elevated risk for long-term neurological sequelae. Mounting evidence suggests that circulating brain-reactive autoantibodies, generated following CNS injury, may serve as both biomarkers of cumulative damage and drivers of secondary neuroinflammation. In this study, we compared circulating autoantibody profiles in military breachers ( = 18) with extensive blast exposure against unexposed military controls ( = 19).

View Article and Find Full Text PDF

Prominent efficacy and good safety of sequential CD19 and CD22 CAR-T therapy in relapsed/refractory adult B-cell acute lymphoblastic leukemia.

Exp Hematol Oncol

January 2025

Bone Marrow Transplantation Center of The First Affiliated Hospital Liangzhu Laboratory, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, Zhejiang, China.

Background: Sequential CD19 and CD22 chimeric antigen receptor (CAR)-T cell therapy offers a promising approach to antigen-loss relapse in relapsed/refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL); however, research in adults remains limited.

Methods: This study aimed to evaluate the efficacy and safety of sequential CD19 and CD22 CAR-T cell therapy in adult patients with R/R B-ALL between November 2020 and November 2023 (ChiCTR2100053871). Key endpoints included the adverse event incidence, overall survival (OS), and leukemia-free survival (LFS).

View Article and Find Full Text PDF
Article Synopsis
  • Recent autopsy studies show that interface astroglial scarring (IAS) can occur at the gray-white matter junction in military personnel who experience repeated blast brain injuries.
  • There is currently no neuroimaging test available to detect IAS, making it difficult to diagnose and treat these injuries.
  • In a study of 27 U.S. Special Operations Forces personnel, five individuals (18.5%) showed elevated neuroinflammation signals at the gray-white matter interface compared to healthy controls, suggesting that TSPO PET scans may help identify repeated blast brain injury.
View Article and Find Full Text PDF

Clinical staging (CS) and tumor burden (TB) play a significant role in FL prognosis and direct its up-front therapy. The aim of this study is to report prognostic factors and clinical outcomes in newly-diagnosed FL patients stratified according to CS and TB in early-stage (ES) disease, advanced-stage with low tumor burden (AS-LTB) and advanced-stage with high tumor burden (AS-HTB). Two hundred fourteen patients with FL grades 1-3A had baseline clinical characteristics and outcomes assessed.

View Article and Find Full Text PDF

A multifactorial risk scoring system for the prediction of early relapse in CMML patients with allo-HSCT: a nationwide representative multicenter study.

Bone Marrow Transplant

November 2024

Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.

Article Synopsis
  • Chronic myelomonocytic leukemia (CMML) is a type of blood cancer where allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently the only curative treatment, although not suitable for all patients, and relapse is a common issue.
  • A nationwide study analyzed data from 238 CMML patients who underwent allo-HSCT across 27 medical centers and 307 patients from a research database to establish a risk scoring system to predict early relapse based on certain prognostic factors.
  • Four key factors were identified that significantly increased the risk of relapse: bone marrow blasts over 10%, age greater than 60 years, low hemoglobin levels, and specific gene mutations, leading to a scoring system that categor
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!