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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288461PMC
http://dx.doi.org/10.1177/00185787231155839DOI Listing

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Article Synopsis
  • The study investigated changes in opioid prescribing patterns for breast cancer patients after the 2014 federal reclassification of hydrocodone, which has raised concerns about adequate pain management.
  • Analysis of data from over 60,000 patients revealed that those who underwent surgery in 2015 and 2016 were significantly less likely to receive prescription opioids for varying durations compared to patients treated in 2013.
  • The findings suggest that federal opioid policies may negatively impact pain management for cancer patients, highlighting the need for inclusive stakeholder engagement in future policy discussions.
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Impact of hydrocodone reclassification on analgesic prescribing in the Veterans Health Administration.

Am J Health Syst Pharm

May 2019

Department of Pharmacy Services, Iowa City VA Healthcare System, Iowa City, IA, and Center for Comprehensive Access and Delivery Research and Evaluation, Iowa City VA Healthcare System, Iowa City, IA.

Purpose: The impact of hydrocodone reclassification on analgesic prescribing in the Veterans Health Administration (VHA) was quantified.

Methods: In this retrospective observational study, the volume of opioid medication dispensed was calculated quarterly from October 2011 to September 2015 using national VHA administrative data. Four volume measures were examined (prescription count, tablets dispensed, days' supply dispensed, and unique patients) for 4 opioid groups: hydrocodone combination products (HCPs), other opioid combination products, tramadol, and single-agent Schedule II opioids.

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Decline in opioid prescribing after federal rescheduling of hydrocodone products.

Pharmacoepidemiol Drug Saf

May 2018

Department of Internal Medicine and Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX, 77555-0177, USA.

Purpose: To examine differences in opioid prescribing by patient characteristics and variation in hydrocodone combination product (HCP) prescribing attributed to states, before and after the 2014 Drug Enforcement Administration's reclassification of HCP from schedule III to the more restrictive schedule II.

Methods: We used 2013 to 2015 data for 9 202 958 patients aged 18 to 64 from a large nationally representative commercial health insurance program to assess the temporal trends in the monthly rate of opioid prescribing.

Results: HCP prescribing decreased by 26% from June 2013 to June 2015; the rate of prescriptions for any opioid decreased by 11%.

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Article Synopsis
  • Opioid regulations in the US have tightened recently due to increased awareness of the prescription epidemic, potentially influencing doctors' prescribing habits.
  • Data was analyzed from 750 patients at MD Anderson Cancer Center's outpatient palliative care clinic, revealing changes in opioid prescription types and doses from 2010 to 2015.
  • The study found a significant decrease in the median morphine equivalent daily dose (MEDD) from 78 mg/d in 2010 to 40 mg/d in 2015 and an increase in tramadol prescriptions following hydrocodone's reclassification as a schedule II opioid.
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