The dynamics of basic and applied research at university and industry have steadily changed since the Eighties, with the private sector reducing its investments in science and universities experiencing significant remodelling in the governance of their funding. While studies have focussed on documenting these changes in industry, less attention has been paid to observe the trajectories of basic and applied research in universities. This work contributes to fill this gap by looking at the evolution of publicly funded research that has been patented by universities between 1978 and 2015. First, we adopt a critical perspective of the basic versus applied dichotomy and identify patents according to three typologies of research: basic, mission-oriented, and applied research. Second, we describe the evolution of these three typologies in universities compared to industry. Our results show that over the years, patents from academic research that was publicly funded have become more oriented towards pure basic research, with mission-oriented basic research and pure applied research decreasing from the late 1990s. These results complement and extend the literature on basic and applied research dynamics in the private sector. By introducing mission-oriented research as a type of basic research with consideration of use, the work problematises the basic and applied research dichotomy and provides insights into the evolution of academic research focus, offering a more complex picture of how university research contributes to industry and broader social value creation.
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http://dx.doi.org/10.1007/s10961-023-10001-5 | DOI Listing |
Front Hum Neurosci
January 2025
Department of Neuroscience and Neurorehabilitation, IRCCS San Raffaele Roma, Rome, Italy.
Over the last four decades, non-invasive brain stimulation techniques (NIBS) have significantly gained interest in the fields of cognitive sciences and dementia care, including neurorehabilitation, for its emerging potential in increasing the insights over brain functions and in boosting residual cognitive functions. In the present paper, basic physiological and technical mechanisms and different applications of NIBS were reviewed and discussed to highlight the importance of NIBS in multidisciplinary and translational approaches in clinical and research settings of cognitive sciences and neurodegenerative diseases, especially in Alzheimer's disease. Indeed, NIBS strategies may represent a promising opportunity to increase the potential of neuromodulation as efficacious interventions for individualized patients care.
View Article and Find Full Text PDFOpen Access J Sports Med
January 2025
Brainnet, Faculty of Applied Sciences, Simon Fraser University, Metro Vancouver, BC, Canada.
Introduction: Athletic peak performance is increasingly focused on cognitive and mental factors. In the current study, cognitive performance was measured by neurophysiological responses in elite Junior-A hockey players.
Methods: Neurophysiological brain vital signs were extracted from event-related potentials (ERPs) to evaluate auditory sensation (the N100), basic attention (the P300), and cognitive processing (the N400).
Iran J Basic Med Sci
January 2025
Molecular Medicine Research Center, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Objectives: Ischemia/reperfusion (IR)-induced ventricular arrhythmia, which mainly occurs after the opening of coronary artery occlusion, poses a clinical problem. This study aims to investigate the effectiveness of pretreatment with coenzyme Q (CoQ) in combination with mitochondrial transplantation on IR-induced ventricular arrhythmias in aged rats.
Materials And Methods: Myocardial IR induction was performed by left anterior descending coronary artery occlusion for 30 min, followed by re-opening for 24 hr.
J Med Life
December 2024
Department of Basic Sciences, College of Science and Health Professions (COSHP), King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Jeddah, Saudi Arabia.
The risk of cardiovascular disease differs among various ethnic groups, highlighting disparities in cardiovascular health among different populations. While multiple studies from other countries have looked at changes in physiological parameters during autonomic function tests like isometric handgrip and cold pressor tests, no correlational research has been done in Saudi Arabia. This lacuna underscores the importance of examining the relationship between cardiorespiratory parameters in young Saudi Arabian individuals during these tests.
View Article and Find Full Text PDFJ Alzheimers Dis
January 2025
The Key Laboratory of Optimal Utilization of Natural Medicine Resources, School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects elderly individuals across the globe. While genetic, environmental, and lifestyle factors are known to influence the onset of AD, the underlying mechanisms remain unclear.
Objective: To elucidate the intricate interplay between metabolites and immune cell activation in the ethology of AD, and to determine their collective impact on AD risk.
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