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http://dx.doi.org/10.1007/s00330-023-09820-9 | DOI Listing |
J Hematol Oncol
December 2024
Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.
Respir Res
December 2024
University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, UK.
To optimize patient outcomes, healthcare decisions should be based on the most up-to-date high-quality evidence. Randomized controlled trials (RCTs) are vital for demonstrating the efficacy of interventions; however, information on how an intervention compares to already available treatments and/or fits into treatment algorithms is sometimes limited. Although different therapeutic classes are available for the treatment of chronic obstructive pulmonary disease (COPD), assessing the relative efficacy of these treatments is challenging.
View Article and Find Full Text PDFBMC Oral Health
December 2024
Department of Chemistry, College of Science, Kuwait University, Safat, P.O. Box 5969, Kwait City, 13060, Kuwait.
BMC Womens Health
December 2024
Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
BMC Med Res Methodol
December 2024
Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
Background: The choice of a single primary outcome in randomised trials can be difficult, especially in mental health where interventions may be complex and target several outcomes simultaneously. We carried out a systematic review to assess the quality of the analysis and reporting of multiple outcomes in mental health RCTs, comparing approaches with current CONSORT and other regulatory guidance.
Methods: The review included all late-stage mental health trials published between 1st January 2019 to 31st December 2020 in 9 leading medical and mental health journals.
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