AI Article Synopsis
- - SARS-CoV-2 has higher mortality rates in older individuals, particularly men with comorbidities like hypertension, diabetes, and obesity, leading to the study's focus on older patients with COVID-19.
- - A study analyzed 128 hospitalized patients (average age 73, mostly men) to assess their health characteristics, revealing 72% had two or more comorbidities, with 42% requiring intensive care and an overall mortality rate of 26.6%.
- - The study found that arterial hypertension and prior institutionalization significantly predicted in-hospital mortality, while age became a less relevant factor when other conditions were considered.
Article Abstract
Background: SARS-CoV-2 affects all age groups, but higher mortality rates are recorded in older people, men and with comorbidities, mainly hypertension, diabetes and obesity.
Aim: To describe the main clinical characteristics, evolution and prognostic factors for death in older patients hospitalized for COVID-19.
Materials And Methods: Retrospective analysis of 128 patients aged 73 years, 66% men, hospitalized at a clinical hospital, with a diagnosis of COVID-19, admitted from May 1 to August 1, 2020. Data were collected from the clinical records, a description of the study population was made, and a univariate analysis and logistic regression were performed.
Results: Seventy-two percent of patients had two or more comorbidities, mainly arterial hypertension in 66%, diabetes mellitus in 34% and cardiovascular disease in 19%. Forty-one percent were admitted to intensive care and 31% were connected to mechanical ventilation. In-hospital mortality was 26.6%. A multivariate analysis was performed in two blocks, finding in the first that arterial hypertension and older age significantly predict mortality. However, when previous institutionalization and immuno-suppression were included as variables in the second block, age ceased to be a significant predictor.
Conclusions: Prognostic factors associated with death in this age group are arterial hypertension and previous institutionalization.
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| http://dx.doi.org/10.4067/S0034-98872022000901145 | DOI Listing |
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