Therapeutic contact lens-related infection by a novel pathogenic fungus Coniochaeta hoffmannii-a case report.

Indian J Med Microbiol

Biofilm and Bioprocess Laboratory, Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli-627012, Tamilnadu, India. Electronic address:

Published: September 2023

AI Article Synopsis

  • * The patient, who had pseudophakic bullous keratopathy, experienced unexpected vision loss after four months of BCL treatment meant to alleviate pain.
  • * Investigations, including a slit-lamp examination and microbial testing of the removed BCL, confirmed the presence of the fungus using Sanger sequencing for precise identification.

Article Abstract

This study aims to report a rare instance of corneal decompensation brought on by Coniochaeta hoffmannii fungus invasion of a bandage contact lens (BCL). A 71-year-old man with pseudophakic bullous keratopathy (PBK) had BCL treatment for four months to symptomatically reduce pain and itching in his right eye. However, the patient unexpectedly lost his vision. The slit-lamp examination revealed an edematous cornea; the extensive direct inspection raised suspicion of BCL. For morphological characterization, the BCL extracted was inoculated onto 5% sheep blood agar and PDA. By Sanger sequencing method the isolate's genomic DNA was molecularly identified as C. hoffmannii.

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http://dx.doi.org/10.1016/j.ijmmb.2023.02.004DOI Listing

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