In this study, to identify bioactive components of Olea europaea leaves extract (OLE), chemometrics analyses including bivariate correlation analysis and partial least squares regression were used to establish the relationships between the chromatograms and anti-photoaging effect of OLE samples. Firstly, the fingerprint of olive leaves extract was determined by high-performance liquid chromatography (HPLC). Photoaging models of HaCaT cells were established by UVB irradiation. The photoaging resistance of OLE was evaluated by cell viability using the MTT assay. Chemometrics analyses showed that compounds 14, 19, 20, 24, 26, and 28 might be the major anti-photoaging components of OLE. Furthermore, after separation by HSCCC and NMR identification, compound 19 is luteoloside and compound 24 is oleuropein. Oleuropein and luteoloside were docked with collagenase (MMP-1), stromelysin (MMP-3), and gelatinase (MMP-9), respectively. The results showed that oleuropein and luteoloside inhibited their activity by directly interacting with MMP-1, MMP-3, and MMP-9, thereby exhibiting anti-photoaging activity. The current bioassay and spectrum-effect relationships are proper for associating sample quality with the active ingredient, and our finding would provide foundation and further understanding of the quality evaluation and quality control of Olea europaea.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jchromb.2023.123807 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Flaxseed and olive oil effectively treat numerous diseases and health conditions, particularly metabolic disorders. Traditional medicine has used both oils for managing cardiovascular disease, diabetes, gastrointestinal dysfunctions, metabolic-dysfunction-associated fatty liver disease (MAFLD), obesity, and more. This review explores the bioactive and polyphenolic compounds in flaxseed and olive oils that provide anti-inflammatory, antioxidant, anti-microbial, hepatoprotective, cardioprotective, antidiabetic, and gastroprotective benefits.
View Article and Find Full Text PDFCircadian- and Light-Driven Rhythmicity of Interconnected Gene Networks in Olive Tree.
Int J Mol Sci
January 2025
Research Centre for Olive, Fruit and Citrus Crops, Council for Agricultural Research and Economics (CREA), Via Settimio Severo 83, 87036 Rende, CS, Italy.
A circadian clock (CC) has evolved in plants that synchronizes their growth and development with daily and seasonal cycles. A properly functioning circadian clock contributes to increasing plant growth, reproduction, and competitiveness. In plants, continuous light treatment has been a successful approach for obtaining novel knowledge about the circadian clock.
View Article and Find Full Text PDFEvaluating the effect of noise reduction strategies in CT perfusion imaging for predicting infarct core with deep learning.
Neuroradiol J
January 2025
Canon Stroke and Vascular Research Center, University at Buffalo, Buffalo, NY, USA.
This study evaluates the efficacy of deep learning models in identifying infarct tissue on computed tomography perfusion (CTP) scans from patients with acute ischemic stroke due to large vessel occlusion, specifically addressing the potential influence of varying noise reduction techniques implemented by different vendors. We analyzed CTP scans from 60 patients who underwent mechanical thrombectomy achieving a modified thrombolysis in cerebral infarction (mTICI) score of 2c or 3, ensuring minimal changes in the infarct core between the initial CTP and follow-up MR imaging. Noise reduction techniques, including principal component analysis (PCA), wavelet, non-local means (NLM), and a no denoising approach, were employed to create hemodynamic parameter maps.
View Article and Find Full Text PDFMale seminal fluid allocation according to socio-sexual context in the South American fruit fly.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol
January 2025
Laboratorio de Investigaciones Ecoetológicas de Moscas de la Fruta y sus Enemigos Naturales (LIEMEN), División Control Biológico de Plagas, PROIMI-Biotecnología, CONICET, Avenida Belgrano y Pasaje Caseros s/n, San Miguel de Tucumán, Tucumán, 4000, Argentina.
During copulation male insects transfer sperm and seminal fluids, including accessory gland proteins (Acps) to females, produced in the accessory glands (AGs). These Acps influence female behavior and physiology, inhibiting sexual receptivity, promoting ovulation and/or oviposition. The theory of ejaculate allocation postulates that production is costly; therefore, males strategically allocate ejaculates based on perception of sperm competition and quality and availability of females.
View Article and Find Full Text PDFCan a Light Detection and Ranging (LiDAR) and Multispectral Sensor Discriminate Canopy Structure Changes Due to Pruning in Olive Growing? A Field Experimentation.
Sensors (Basel)
December 2024
Department of Agricultural, Alimentary, Environmental and Forestry Sciences, Biosystem Engineering Division-DAGRI, University of Florence, Piazzale delle Cascine 15, 50144 Florence, Italy.
The present research aimed to evaluate whether two sensors, optical and laser, could highlight the change in olive trees' canopy structure due to pruning. Therefore, two proximal sensors were mounted on a ground vehicle (Kubota B2420 tractor): a multispectral sensor (OptRx ACS 430 AgLeader) and a 2D LiDAR sensor (Sick TIM 561). The multispectral sensor was used to evaluate the potential effect of biomass variability before pruning on sensor response.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!