AI Article Synopsis
- The study investigated the effects of COVID-19 on patients with abnormal liver and kidney function, analyzing data from 289 individuals using PCR for infection detection.
- Results showed that patients exhibited elevated levels of liver enzymes (AST and ALT) and creatinine, with men having approximately 4.28 times and women around 2.18 times higher creatinine levels than the reference values.
- The findings suggest that high creatinine levels could potentially indicate a greater risk for severe COVID-19 outcomes.
Article Abstract
Goal -the existing data on the coronavirus disease 2019 (COVID-19) revealed the impact of the disease on different organs such as the liver, the heart, the kidneys, etc. In our study, we evaluated the clinical characteristics of COVID-19 in patients with abnormal liver and kidney test results in recovered and dead patients. The number of the covid-19 patients was - 289. The gold standard method of polymerase chain reaction (PCR) was used to detect the infection of Covid-19. Blood plasma was used as research material. For The Determination of ALT, AST, and Creatinine, the Analyzer was the Prestige 24i - optimized, modified method according to the International Federation of Clinical Chemistry (IFCC), without pyridoxal phosphate; For the statistical analysis were used the Graphed Prism (Version 8.0). Studies have revealed an increase in AST and ALT compared with the reference value. A small difference was also found between those who died and those who recovered; A change in creatinine levels was also found. Men have a high level of Creatinine (~4.28 times) compared to the reference level, and in women, the level of Creatinine is ~2.18 times higher than the reference level. We have thought that according to our results, the high creatinine levels may have some risk impact for the severity of COVID-19 disease.
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