AI Article Synopsis
- - Rheumatoid arthritis (RA) is a chronic inflammatory condition affecting 1-2% of adults, characterized by symmetrical joint pain and an increased mortality rate over time, especially after 15 years of the disease.
- - A study conducted on 100 RA patients in Bikaner, India, found that 38% had pulmonary manifestations, with interstitial lung disease (ILD) being the most common finding on high-resolution computed tomography (HRCT).
- - The findings suggest that RA patients, particularly older males with comorbidities and longer disease duration, should be regularly screened for lung issues using chest X-rays, pulmonary function tests (PFT), and HRCT when necessary.
Article Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology marked by symmetric, peripheral polyarthritis. RA has a prevalence of 1-2% in the general adult population. The mortality rate in patients with RA increases during the course of the disease, with a tendency to accelerate after 15 yearsAim: To study the pulmonary manifestations and their severity using [Disease Activity Score (DAS)-28 score] in patients of RAMaterials and methods: Present study was conducted in the Department of Medicine, Sardar Patel Medical College and Associated Group of Hospitals Bikaner, Bikaner, Rajasthan, India, on 100 patients. This study was a cross-sectional, observational study conducted over 1 year. Consecutive cases of RA patients attending the outpatient department or admitted to the medicine wards were selected according to the inclusion and exclusion criteriaResults: Pulmonary manifestation was present in a total of 38% of cases, while the remaining 62% of cases had no pulmonary manifestation. The presence of comorbidity and C-reactive protein (CRP) was significantly associated with pulmonary manifestation in RA patients. On high-resolution computed tomography (HRCT), the most common finding was interstitial lung disease (ILD) (60.5%), with usual interstitial pneumonia (UIP) as the most common pattern. On performing a pulmonary function test (PFT), 33 patients (86.84%) had an abnormal result, with restrictive as the most common patternConclusion: The patients of RA, especially those with advanced age, long duration of disease, male sex, and associated comorbidity, should be screened for pulmonary complications of RA using X-ray chest and PFT, supplemented by HRCT chest wherever required.
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| http://dx.doi.org/10.5005/japi-11001-0195 | DOI Listing |
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