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http://dx.doi.org/10.1007/s10396-023-01339-2 | DOI Listing |
Eur J Nucl Med Mol Imaging
January 2025
Institute of Radiation Medicine, Fudan University, Xietu Road 2094, Shanghai, 200032, China.
Objectives: Mesothelin (MSLN) is an antigen that is overexpressed in various cancers, and its interaction with tumor-associated cancer antigen 125 plays a multifaceted role in tumor metastasis. The serum MSLN expression level can be detected using enzyme-linked immunosorbent assay; however, non-invasive visualization of its expression at the tumor site is currently lacking. Therefore, the aim of this study was to develop a molecular probe for imaging MSLN expression through positron emission tomography (PET).
View Article and Find Full Text PDFIran J Basic Med Sci
January 2025
Faculty of Medical Sciences, Ardabil, Iran.
Objectives: Increased nuclear factor (NF-kβ) and carbonyl stress due to decreased glyoxalase-1 activity (Glo-I) contribute significantly to insulin resistance and vascular complications. Therefore, we aimed to study the impact of the combination of thiamine and niacin on hepatic NF-kβ signaling, metabolic profile, and Glo-I activity in male rats with type-2 diabetes (T2DM).
Materials And Methods: Forty male rats were divided equally into five groups: control, diabetic, diabetic treated with thiamine (180 mg/l in drinking water), niacin (180 mg/l), and a combination of both.
Coherent heterodyne lidars are typically used for windspeed and attenuated backscattering measurements. The lack of molecular backscattering detection capability has limited the calibrated backscattering measurements until recent advances in coherent lidar technology. In this work, the simultaneous detection of aerosol and molecular backscattering is demonstrated with coherent heterodyne lidar, and the results are compared with a state-of-the-art Raman lidar PollyXT as a reference in a long-range for the first time.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Prothodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China.
Nature
January 2025
State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Fujian, China.
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