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Treatment of very high risk membranous nephropathy complicated by pulmonary embolism with glucocorticoids and rituximab: Case report.
Medicine (Baltimore)
January 2025
Division of Nephrology, Department of Medicine, National University Hospital, Singapore.
Rationale: We report the efficacy of combination prednisolone and intravenous (IV) rituximab as an immunosuppressive regimen for a young male presenting with extensive venous thromboembolism including a submassive pulmonary embolism secondary to life-threatening nephrotic syndrome from very high risk anti-phospholipase-A2 receptor (PLA2R) positive membranous nephropathy. Initial treatment was with mechanical thrombectomy and anticoagulation. Thereafter, oral prednisolone was initiated to induce remission, during a period of uninterrupted anticoagulation.
View Article and Find Full Text PDFAn Early-Stage Economic Evaluation of Superabsorbent Wound Dressings for the Management of Moderately to Highly Exuding Leg Ulcers in Slovakian Settings.
Adv Skin Wound Care
January 2025
At Paul Hartmann AG, Heidenheim, Germany, Vladica M. Veličković, MD, is Head of Evidence Generation; Anna Serafin, PhD, is Senior Project Manager Clinical Investigation; Yana Arlouskaya, MS, is Project Manager Clinical Investigations; and Thurid-Christiane Milde, MBA, is Senior Manager Global HEOR Support, Wound Care. Beáta Grešš Halász, PhD, is Lecturer, Department of Nursing, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Košice, Slovakia.
Background: The management of chronic leg ulcers, including venous leg ulcers (VLUs), causes a considerable economic and clinical burden to healthcare systems. Factors such as nursing time, hospital care, and wound dressings account for approximately 85% of the total cost. Superabsorbent dressings (eg, superabsorbent polymers [SAPs]) are recommended as a first-line treatment for moderately to highly exuding VLUs.
View Article and Find Full Text PDFA Curious Case of Scimitar Syndrome That Defies Embryology.
Ann Thorac Surg Short Rep
December 2024
Department of Pediatric Cardiac Surgery, Cleveland Clinic, Cleveland, Ohio.
Scimitar syndrome is a rare condition described by unique anatomic features that consist mainly of an abnormal connection of the right pulmonary veins to the inferior vena cava and right atrial junction, as well as an anomalous systemic arterial supply to the right lung. We present the case of a 60-year-old man with an atypical variant of scimitar syndrome that was embryologically perplexing and anatomically challenging to correct. We highlight key surgical and procedural considerations for a patient with scimitar syndrome presenting with this complex surgical anatomy.
View Article and Find Full Text PDFMethodology of INDICATE: Investigating Neuromarkers for Decline & Impairment of Cognition After Thrombectomy for ELVO.
Alzheimers Dement
December 2024
University of Kentucky, Lexington, KY, USA
Background: Vascular cognitive impairment and dementia (VCID) is present in 25‐30% of stroke patients, and a need exists to develop predictive biomarkers to identify patients that will incur chronic cognitive impairment. The National Plan to Address Alzheimer’s Disease and the NHLBI‐NINDS VCID Workshop called for increased research on VCID prediction, especially in underserved populations. Our stroke patient population is comprised of 70% from Appalachian areas, part of US Stroke Belt, so we are uniquely situated to perform this study.
View Article and Find Full Text PDFThe Impact of Inferior Vena Cava Anomalies on Deep Vein Thrombosis: A Case Report.
Cureus
December 2024
Cardiology, Lower Bucks Hospital, Bristol, USA.
Inferior vena cava (IVC) anomalies are rare congenital pathologies related to variations of agenesis, hypoplasia, or atresia, predisposing patients to thromboembolic events secondary to an alteration in venous drainage with resultant stasis. This is a case report of a 27-year-old male without significant medical history presenting for a fall after playing recreational basketball with associated pain and swelling in his left lower extremity. After his symptoms progressively worsened, he came to the emergency room for an evaluation where an ultrasound (US) of the extremity showed extensive deep vein thromboses (DVT).
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