Different property enhancement techniques have already been established to support upcycling of construction and demolition waste as aggregate in concrete. However, the most suitable and sustainable method is still unknown. Quality improvement of recycled coarse aggregate (RCA) after any treatment method and its environmental impact is estimated using life cycle analysis (LCA). This article compares the environmental impacts of such treatment methods on RCA and aims to find out the most suitable method with minimum impacts. The functional unit of this study is considered the preparation of 1 tonne of treated aggregate (recycled), considering reduction in water absorption after the treatment. An LCA is carried out using the SimaPro software (https://simapro.com/) followed by ISO 14040/44 guidelines. Based on the LCA environmental profiles, thermal treatment is the highest emission contributing removal method followed by mechanical grinding. In strengthening of attached mortar methods, accelerated carbonation process is the major emission contributing method followed by a specific microbial treatment. Moreover, a sensitivity analysis was performed by varying the energy mix with a focus on renewable-based energy mix. The sensitivity analysis shows a shift on selection for the suitable treatment method and other possibilities considering renewable-based energy mix. A preliminary assessment and probable impact prediction could be conceptualized before the adoption of any treatment method on RCA for a particular location.
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http://dx.doi.org/10.1177/0734242X231180651 | DOI Listing |
Pol J Vet Sci
December 2024
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kyungpook National University, 80 Daehak-ro, Daegu, 41566, Korea.
Mupirocin is an effective antibiotic for infectious skin diseases. However, mupirocin is formulated as an ointment and is difficult to apply in canine systemic pyoderma. Therefore, many clinicians reformulate mupirocin off-label ointment into a spray.
View Article and Find Full Text PDFCNS Neurosci Ther
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Department of Functional Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Background: Patients with disorders of consciousness (DOC) undergoing spinal cord stimulation (SCS) for arousal treatment require an assessment of their conscious state before and after the procedure. This is typically evaluated using behavioral scales (CRS-R), but this method can be influenced by the subjectivity of the physician. Event-related potentials (ERP) and EEG power spectrum are associated with the recovery of consciousness.
View Article and Find Full Text PDFFront Biosci (Schol Ed)
December 2024
Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
Background: Alternative cleavage and polyadenylation (APA) is a crucial post-transcriptional gene regulation mechanism that regulates gene expression in eukaryotes by increasing the diversity and complexity of both the transcriptome and proteome. Despite the development of more than a dozen experimental methods over the last decade to identify and quantify APA events, widespread adoption of these methods has been limited by technical, financial, and time constraints. Consequently, APA remains poorly understood in most eukaryotes.
View Article and Find Full Text PDFFront Biosci (Elite Ed)
October 2024
Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, 1983969411 Tehran, Iran.
Background: Regenerative endodontics requires an innovative delivery system to release antibiotics/growth factors in a sequential trend. This study focuses on developing/characterizing a thermoresponsive core-shell hydrogel designed for targeted drug delivery in endodontics.
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Front Biosci (Landmark Ed)
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Department of Immunology, Institute of Biomedical Research Universidad Nacional Autónoma de México, UNAM, 04510 Mexico City, Mexico.
Background: Multiple sclerosis (MS) is a demyelinating, neuroinflammatory, progressive disease that severely affects human health of young adults. Neuroinflammation (NI) and demyelination, as well as their interactions, are key therapeutic targets to halt or slow disease progression. Potent steroidal anti-inflammatory drugs such as methylprednisolone (MP) and remyelinating neurosteroids such as allopregnanolone (ALLO) could be co-administered intranasally to enhance their efficacy by providing direct access to the central nervous system (CNS).
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