Context: Anticariogenic properties have been ascribed to polyphenolic compounds present in high concentrations in numerous fruits. Berries, in particular, have been reported as potentially having an inhibitory effect on the dental biofilm and subsequently on caries, but the evidence is unclear.
Objective: The objective of this review was to explore the literature and summarize the evidence for berries having an inhibitory effect on the dental biofilm and an anticariogenic effect.
Data Sources: Following Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, the PubMed, Web of Science, and SCOPUS databases were scanned using predefined and accessible terms, with a search strategy based on a structured PICO question.
Data Extraction: After article selection, 23 studies met the inclusion criteria, most of them being in vitro studies. A risk assessment was performed, and data were extracted and presented in a table for qualitative analysis.
Data Analysis: Meta-analyses were conducted using standardized mean differences (SMDs) with a 95% confidence interval (CI) by Review manager 5.4.
Results: Only 3 types of berries were found to have a reported anticaries effect: grape seed extract (GSE), cranberry, and sour cherry. Nine studies that fulfilled the eligibility criteria were subjected to quantitative analysis. Meta-analyses showed GSE was associated with enhanced remineralization of dental enamel (SMD = .96 95% CI [.45, 1.46], P < .0002) and of dentin (SMD = .65 95% CI [.13, 1.17], P = .01). Cranberry extracts positively influenced the cariogenic dental biofilm by decreasing the biofilm biomass (SMD = -2.23 95% CI [-4.40, -.05], P = .04), and biovolume (SMD = -2.86 95% CI [-4.34, -1.37], P = .0002), and increasing the biofilm pH (SMD = 7.9 95% CI [3.49, 12.31], P < .0004).
Conclusion: Within the limitations of this systematic review and metaanalysis, GSE and cranberries or their active compounds could represent an alternative for caries management. Further clinical trials are needed to verify this effect in a clinical setting.
Systematic Review Registration: PROSPERO registration no. CRD42020223579.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/nutrit/nuad063 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS-A multicentre case-control study.
Sci Rep
January 2025
Clinical Infection, Microbiology & Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
It is established that patients hospitalised with COVID-19 often have ongoing morbidity affecting activity of daily living (ADL), employment, and mental health. However, little is known about the relative outcomes in patients with COVID-19 neurological or psychiatric complications. We conducted a UK multicentre case-control study of patients hospitalised with COVID-19 (controls) and those who developed COVID-19 associated acute neurological or psychiatric complications (cases).
View Article and Find Full Text PDFFitness, Body Composition, and Health Behaviors in Long-Term Survivors of Adolescent and Young Adult Cancers.
J Adolesc Young Adult Oncol
January 2025
Deakin University, Institute for Physical Activity and Nutrition (IPAN), Geelong, Australia.
To investigate cardiorespiratory fitness (CRF), body composition, health behaviors, and health-related quality of life (HRQoL) in adolescent and young adult cancer survivors (AYA-CS) compared with age-matched counterparts without a cancer diagnosis. This cross-sectional study recruited participants aged 15-25 years at the time of their cancer diagnosis and ≥ 5 years post-treatment. Participants completed cardiopulmonary exercise testing, dual-energy X-ray absorptiometry, food diaries, physical activity (PA), fatigue, and HRQoL questionnaires.
View Article and Find Full Text PDFEvaluation of integrated polysaccharide, biopolymers and clay composite membranes for clarification process of citrus fruit (sweet lime) juice.
Int J Biol Macromol
January 2025
Advanced Membrane Technology Research Centre (AMTEC), Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia.
This study focuses on the development of an efficient membrane-based clarification process to enhance the performance of subsequent ultrafiltration and produce high-quality sweet lime juice. A range of casting solutions were prepared using a blend of pore-forming polymers, including polyvinylpyrrolidone (PVP), polyvinylidene fluoride (PVDF), and cellulose acetate (CA), dissolved in dimethylformamide (DMF) solvent through the phase inversion technique. To further enhance the membrane's performance, four biopolymers poly (lactic acid) (PLA), xanthan gum, chitosan, and gelatin were incorporated, with and without clay, to refine its structure, porosity, and surface properties.
View Article and Find Full Text PDFPreparation and characterization of polyvinyl alcohol and chitosan composite film with cassia oil encapsulated in β-cyclodextrin and its application in fresh banana.
Int J Biol Macromol
January 2025
Institute of Translational Medicine, School of Medicine, Yangzhou University, Yangzhou 225001, PR China; The Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225001, PR China. Electronic address:
In this study, composite films were developed by encapsulating cassia oil (CO) with β-cyclodextrin through a microencapsulation technique and incorporating it into a chitosan (CS), polyvinyl alcohol (PVA) and glycerol matrix. The primary objective of the film was to inhibit bacterial growth on the surface of fresh bananas and extend their shelf life. Characterization methods were employed to evaluate the physical properties and functionality of the composite films.
View Article and Find Full Text PDFAn intelligent bilayer film based on blue honeysuckle berries and Artemisia Sphaerocephala Krasch. Gum for Cyprinus carpio preservation and indication.
Int J Biol Macromol
January 2025
College of Engineering and Technology, Northeast Forestry University, Harbin 150040, PR China. Electronic address:
The demand for extended shelf life and food safety in the food industry continues to rise. At the same time, the environmental burden of traditional plastic packaging materials is becoming increasingly serious. Therefore, in this study, an intelligent bilayer film with a pH-sensitive inner indicator film based on Artemisia Sphaerocephala Krasch.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!