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Histologic Features of Mycobacterial Spindle Cell Pseudotumors: A Multi-institutional Clinicopathologic Analysis of 14 Cases.
Am J Surg Pathol
July 2024
Department of Pathology, University of Michigan, Ann Arbor, MI.
Mycobacterial spindle cell pseudotumors (MSPs) are a rare and diagnostically challenging manifestation of non-tuberculous mycobacterial (NTM) infections. Proper recognition of these pseudotumors is important because they are treatable and benign. In this study, we evaluated the morphologic patterns of MSPs to improve their pathologic identification.
View Article and Find Full Text PDFMycobacterial spindle cell pseudotumor of the spinal cord: Case report and literature review.
J Neuroimmunol
May 2024
Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Medicine, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA. Electronic address:
We report the first description of spinal cord mycobacterial spindle cell pseudotumor. A patient with newly diagnosed advanced HIV presented with recent-onset bilateral leg weakness and was found to have a hypermetabolic spinal cord mass on structural and molecular imaging. Biopsy and cultures from blood and cerebrospinal fluid confirmed spindle cell pseudotumor due to Mycobacterium avium-intracellulare.
View Article and Find Full Text PDFBacillus Calmette-Guérin Vaccine-induced Mycobacterial Spindle Cell Pseudotumor in an Infant.
Pediatr Infect Dis J
February 2024
Respiratory Department II, National Clinical Research Center for Respiratory Diseases, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China, Respiratory Department, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, China.
Mycobacterial Spindle Cell Pseudotumor (MSP): A Case Report.
Cureus
June 2023
Dermatology, University of Florida, Gainesville, USA.
Mycobacterial spindle cell pseudotumor (MSP) is a rare proliferation of spindle-shaped histiocytes that occurs most frequently in lymph nodes but has also been documented in the skin, soft tissue, abdomen, and other sites. These lesions contain acid-fast mycobacteria, most commonly complex. Fewer than 10 cases of cutaneous MSPs have been published, and most have occurred in immunocompromised patients, either due to human immunodeficiency virus (HIV) infection or immunosuppressive medications.
View Article and Find Full Text PDFMycobacterial spindle cell pseudotumor mimicking Richter transformation in a patient with hairy cell leukemia.
Int J Hematol
August 2023
Department of Pathology, Institute of Medical Genetics and Pathology, University Hospital of Basel, University of Basel, Schönbeinstrasse 40, 4031, Basel, Switzerland.
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