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http://dx.doi.org/10.3389/fbioe.2023.1210334 | DOI Listing |
Pharmaceutics
December 2024
Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC 27599, USA.
Background/objectives: Glioblastoma multiforme (GBM) is the most common high-grade primary brain cancer in adults. Despite efforts to advance treatment, GBM remains treatment resistant and inevitably progresses after first-line therapy. Induced neural stem cell (iNSC) therapy is a promising, personalized cell therapy approach that has been explored to circumvent challenges associated with the current GBM treatment.
View Article and Find Full Text PDFSensors (Basel)
January 2025
School of Naval Architecture, Ocean and Energy Power Engineering, Wuhan University of Technology, Wuhan 430070, China.
Remaining useful life (RUL) prediction is a cornerstone of Prognostic and Health Management (PHM) for power machinery, playing a crucial role in ensuring the reliability and safety of these critical systems. In recent years, deep learning techniques have shown great promise in RUL prediction, providing more reliable and accurate outcomes. However, existing models often struggle with comprehensive feature extraction, especially in capturing the complex behavior of power machinery, where non-linear degradation patterns arise under varying operational conditions.
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January 2025
Smart Diagnostic and Online Monitoring, Leipzig University of Applied Sciences, Wächterstraße 13, 04107 Leipzig, Germany.
This paper presents a comparative study of different AI models for indoor positioning systems, emphasizing improvements in localization accuracy and processing time. This study examines Artificial Neural Networks (ANNs), Long Short-Term Memory (LSTM), Recurrent Neural Networks (RNNs), and the Kalman filter using a real Received Signal Strength Indicator (RSSI) and 9-axis ICM-20948 sensor. An in-depth analysis is provided in this paper for data cleaning and feature selection to reduce errors for all the models.
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January 2025
Cognitive Systems Lab, University of Bremen, 28359 Bremen, Germany.
This paper presents an approach for event recognition in sequential images using human body part features and their surrounding context. Key body points were approximated to track and monitor their presence in complex scenarios. Various feature descriptors, including MSER (Maximally Stable Extremal Regions), SURF (Speeded-Up Robust Features), distance transform, and DOF (Degrees of Freedom), were applied to skeleton points, while BRIEF (Binary Robust Independent Elementary Features), HOG (Histogram of Oriented Gradients), FAST (Features from Accelerated Segment Test), and Optical Flow were used on silhouettes or full-body points to capture both geometric and motion-based features.
View Article and Find Full Text PDFGenes (Basel)
January 2025
Department of Ophthalmology, Boston Children's Hospital, Boston, MA 02115, USA.
Background/objectives: Strabismus is the most common ocular disorder of childhood. Three rare, recurrent genetic duplications have been associated with both esotropia and exotropia, but the mechanisms by which they contribute to strabismus are unknown. This work aims to investigate the mechanisms of the smallest of the three, a 23 kb duplication on chromosome 4 (hg38|4:25,554,985-25,578,843).
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