In this multicenter, prospective, test-negative, case-control study in Japan, the effectiveness of both BA.1-containing and BA.4/BA.5-containing bivalent coronavirus disease 2019 mRNA vaccines against symptomatic infection during the BA.5-dominant period was high compared with no vaccination (65% and 76%) and moderate compared with monovalent vaccines administered over half a year earlier (46% combined).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284337PMC
http://dx.doi.org/10.1093/ofid/ofad240DOI Listing

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