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The environmental neuroactive chemicals list of prioritized substances for human biomonitoring and neurotoxicity testing: A database and high-throughput toxicokinetics approach.
Environ Res
February 2025
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, 135 Dauer Drive, CB #7435, Chapel Hill, NC, 27599, USA.
There is a diversity of chemicals to which humans are potentially exposed. Few of these chemicals have linked human biomonitoring data, and most have very limited neurotoxicity testing. Of particular concern are environmental exposures impacting children, who constitute a population of heightened susceptibility due to rapid neural growth and plasticity, yet lack biomonitoring data compared to other age/population subgroups.
View Article and Find Full Text PDFChild health prioritisation in national adaptation policies on climate change: a policy document analysis across 160 countries.
Lancet Child Adolesc Health
July 2024
Heidelberg Institute of Global Health, Heidelberg University Hospital, Heidelberg, Germany; International Health Department, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Integration of child-specific adaptation measures into health policies is imperative given children's heightened susceptibility to the health impacts of climate change. Using a document analysis method, we examined 160 national adaptation policies for inclusion of child-relevant measures and identified 19 child health-related adaptation domains. 44 (28%) of 160 countries' policies that were analysed failed to include any domains, 49 (31%) included at least one child-related domain, 62 (39%) included between two and six domains, and five (3%) included at least seven domains.
View Article and Find Full Text PDFGuidelines for reporting pediatric and child health clinical trial protocols and reports: study protocol for SPIRIT-Children and CONSORT-Children.
Trials
January 2024
Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada.
Background: Despite the critical importance of clinical trials to provide evidence about the effects of intervention for children and youth, a paucity of published high-quality pediatric clinical trials persists. Sub-optimal reporting of key trial elements necessary to critically appraise and synthesize findings is prevalent. To harmonize and provide guidance for reporting in pediatric controlled clinical trial protocols and reports, reporting guideline extensions to the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) and Consolidated Standards of Reporting Trials (CONSORT) guidelines specific to pediatrics are being developed: SPIRIT-Children (SPIRIT-C) and CONSORT-Children (CONSORT-C).
View Article and Find Full Text PDFInclusion of child-relevant data in the development and validation of heat vulnerability indices: a commentary.
Environ Res Health
September 2023
Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, United States of America.
Evaluation of a state-wide intervention on salt intake in primary schoolchildren living in Victoria, Australia.
Public Health Nutr
July 2023
The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
Objective: In 2015, the Victorian Salt Reduction Partnership launched a 4-year multifaceted salt reduction intervention designed to reduce salt intake by 1 g/d in children and adults living in Victoria, Australia. Child-relevant intervention strategies included a consumer awareness campaign targeting parents and food industry engagement seeking to reduce salt levels in processed foods. This study aimed to assess trends in salt intake, dietary sources of salt and discretionary salt use in primary schoolchildren pre- and post-delivery of the intervention.
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