Background: In the previous four decades there have been remarkable changes and development in the approach toward the diagnosis and management of asthma. There are wide variations in the clinical profile of asthma patients in different parts of a vast country like India due to significant variations in the geography, culture, ethnicity, and socioeconomic profile of the Indian population. In the present study, we have aimed to study the clinical profile of adult asthmatic patients in a tertiary care teaching institute in Northern India.
Methods: In this observational cross-sectional study, a total of 966 asthma patients were included from August 2020 to July 2021 after following strict inclusion and exclusion criteria. After a thorough history and clinical examination, patients were subjected to relevant investigations including spirometry.
Results: Our study showed slight female preponderance (51.7%) over males among asthma patients. A maximum number of patients were of comparatively younger age groups and urban. The most common symptom at the time of presentation was breathlessness (94.5%) followed by cough in about 59.8%. Family history was present in about 9.3% of patients. A maximum number of patients presented in the months of November and December and rhinitis was the most commonly associated atopic condition. The majority (65.28%) of previously diagnosed patients had uncontrolled asthma at the time of their first presentation in our department.
Conclusion: Results of our study endorse the poor awareness in society towards education and management of asthma. Females and comparatively younger patients are more commonly affected. Significant differences in our study from previous studies in different parts of India confirm that the pattern and clinical profile of asthma patients in one region cannot be extrapolated to other regions and the need for future studies in other regions of our country is also required.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282159 | PMC |
| http://dx.doi.org/10.7759/cureus.39316 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Application value of surface respiratory muscle electromyography and its ratio to tidal volume in the assessment of airway hyperresponsiveness in bronchial asthma patients].
Zhonghua Yi Xue Za Zhi
January 2025
State Key Laboratory of Respiratory Disease/Guangzhou Institute of Respiratory Health/the First Affiliated Hospital of Guangzhou Medical University, Guangzhou510120, China.
To explore the application value of surface respiratory muscle electromyography and its ratio to tidal volume in the assessment of airway hyperresponsiveness in bronchial asthma patients. A case-control study was conducted to retrospectively analyze the data of 29 asthma patients who visited the outpatient department of respiratory medicine of the First Affiliated Hospital of Guangzhou Medical University from October 2015 to May 2017 and 27 non-asthmatic subjects who were recruited as the control group.Changes in surface respiratory muscle electromyography (parasternal, EMG, diaphragmatic, EMG), and its ratio to tidal volume (EMG/VT, EMG/VT) before and after the histamine challenge test were compared between the asthma group and the control group; and their receiver operating characteristic (ROC) curves were plotted.
View Article and Find Full Text PDFAssociation between polycyclic aromatic hydrocarbons exposure and current asthma: a population-based study.
BMC Public Health
January 2025
Department of Respiratory and Critical Care Medicine, Peking University First Hospital, Beijing, China.
Background: Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants that can cause a variety of health problems. This study sought to determine whether there was a relationship between PAHs and current asthma in adults.
Methods: This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2016 and employed multifactor logistic regression, subgroup analyses, and smoothed curve fitting to examine the linear and nonlinear associations between PAHs and current asthma.
Diagnostic Accuracy of FEF for Bronchial Hyperresponsiveness in Patients with Suspected Asthma and/or Allergic Rhinitis: A Systematic Review and Meta-analysis.
Lung
January 2025
Department of Pathology, The Second People's Hospital of China Three Gorges University/ Yichang Second People's Hospital, Yichang, 443000, Hubei, China.
Background: Some studies have suggested that the forced expiratory flow between 25 and 75% of vital capacity (FEF) can be used as an early marker of bronchial hyperresponsiveness (BHR) in asthma and allergic rhinitis (AR), but is highly variable. Here, we aimed to assess whether the FEF can be used to diagnose BHR in patients with asthma-like symptoms and AR.
Methods: PubMed, EMBASE, Web of Science, Wiley Online Library, Cochrane Library, SinoMed, CNKI, and Wanfang Data were searched to acquire eligible studies.
The Art of Clinical Negotiation.
J Allergy Clin Immunol Pract
January 2025
Dartmouth Hitchcock Medical Center, Section of Allergy and Clinical Immunology, Lebanon, NH; Geisel School of Medicine at Dartmouth, Departments of Medicine and Pediatrics. Electronic address:
The art of clinical negotiation is an important, yet underappreciated aspect of medicine. Key components of negotiation include the need to consider principles over personalities, to explore all options before deciding on the best course, to realize if consensus cannot be achieved then compromise may still be possible, to work from evidence to incorporate contextual factors, and to stay evidence based. These principles can be helpful in many settings, including contract negotiation, drug pricing, and research.
View Article and Find Full Text PDFBackground therapy in severe asthma on monoclonal antibody treatment in Real Life.
Respir Med
January 2025
S.C. Pneumologia, ASL2 Savonese, Savona, Italy. Electronic address:
Background: Global Initiative for Asthma (GINA) recently recommends clinicians to reduce inhaled corticosteroid doses in patients with severe asthma who respond positively to monoclonal antibodies (MAbs).
Objective: As we operated this reduction even before the document, we analysed our cohort of subjects on treatment with a MAbs for at least 24 months.
Methods: Data stored in our electronic archive and at the 6-month follow-up (FU) were registered and patients' adherence to asthma therapy was derived by electronic pharmacy claim database.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!