Millions of affordable healthy homes are needed for the rapidly expanding population of sub-Saharan Africa. This enormous challenge is an opportunity to address pervasive health issues linked to housing, where diseases that most impact children-malaria, diarrhoea and respiratory tract infections-are often acquired. A pilot project in northern Tanzania demonstrated the potential of novel house designs to reduce infectious disease transmission in homes. To conduct a randomized controlled trial of one novel-design house, the research team moved to the southeast of the country. This article describes the challenges experienced during the construction and initial evaluation of the novel house.
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http://dx.doi.org/10.1093/trstmh/trad039 | DOI Listing |
J Phys Chem B
January 2025
Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York 10065, United States.
ModeHunter is a modular Python software package for the simulation of 3D biophysical motion across spatial resolution scales using modal analysis of elastic networks. It has been curated from our in-house Python scripts over the last 15 years, with a focus on detecting similarities of elastic motion between atomic structures, coarse-grained graphs, and volumetric data obtained from biophysical or biomedical imaging origins, such as electron microscopy or tomography. With ModeHunter, normal modes of biophysical motion can be analyzed with various static visualization techniques or brought to life by dynamics animation in terms of single or multimode trajectories or decoy ensembles.
View Article and Find Full Text PDFRadiol Adv
October 2024
Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Purposes: The objective was to evaluate the accuracy of a novel CT dynamic angiographic imaging (CT-DAI) algorithm for rapid fractional flow reserve (FFR) measurement in patients with coronary artery disease (CAD).
Materials And Methods: This retrospective study included 14 patients (age 58.5 ± 10.
J Dairy Sci
January 2025
EthoLab - Applied Ethology and Animal Welfare Lab, Graduate Program in Animal Science, School of Medicine and Life Sciences, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, 80215-901, Brazil. Electronic address:
Pair housing presents an alternative to individual or larger group housing systems, though the effects of different pairing ages on calf welfare are not well understood. In this study, we examined the impact of pairing age on the performance, health, and behavior of dairy calves. A total of 140 Holstein female calves (n = 70 pairs) were used, paired at 3 ages: Early (6-7 d; 48 calves), Intermediate (29-30 d; 48 calves), and Late pairing (49-50 d; 44 calves).
View Article and Find Full Text PDFTransplantation
January 2025
Department of Surgery, CORELAB, University of California, Los Angeles, Los Angeles, CA.
Background: Despite efforts to ensure equitable access to liver transplantation (LT), significant disparities remain. Although prior literature has considered the effects of patient sex, race, and income, the contemporary impact of community socioeconomic disadvantage on outcomes after waitlisting for LT remains to be elucidated. We sought to evaluate the association of community-level socioeconomic deprivation with survival after waitlisting for LT.
View Article and Find Full Text PDFEvid Based Dent
January 2025
Doctoral Research Fellow and Specialty Trainee (Endodontics), School of Dental Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.
Aims: This study aimed to assess the effectiveness of a novel antimicrobial gel, containing copper and silver nanoparticles, for use in root canal disinfection.
Methods: Copper and silver-based gels were created in-house, using a support network of biocompatible polymers, including polyvinyl alcohol (PVA), polyvinyl pyrrolidone (PVP), and polyethylene glycol (PEG). Six experimental groups were created, three containing silver ions and three copper ions, where the PVA, PVP and PEG ratios were also adjusted in each group to test the gel's physical state.
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