Background: Nail apparatus melanoma is a malignant tumor with a high incidence in Chinese melanoma patients. Slow Mohs micrographic surgery is an emerging technique for treating nail apparatus melanoma in situ (NAMIS).
Objective: This study evaluated the efficacy and safety of slow Mohs micrographic surgery for treating NAMIS.
Methods: Patients were enrolled in this retrospective study and treated in a single center from October 1, 2016, to June 30, 2022. Each patient underwent standard slow Mohs micrographic surgery, and follow-up was regularly conducted at clinics.
Results: Ten patients were enrolled in the study. Two patients underwent one Mohs stage, seven underwent two Mohs stages, and one underwent seven Mohs stages. The resection margin ranged from 5 to 25 mm. No severe complications were reported in the treatment, and recurrence of NAMIS was not observed during the follow-up period.
Conclusion: Slow Mohs micrographic surgery is a valuable surgical method to treat NAMIS that preserves digit function and can be well tolerated by patients.
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http://dx.doi.org/10.1111/ijd.16748 | DOI Listing |
Alzheimers Dement
November 2024
Dpartment of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Decades of research have provided evidence that Alzheimer's disease (AD) is caused in part by cerebral accumulation of amyloid beta-protein (Aβ). In 2023, the US Food and Drug Administration gave full regulatory approval to a disease-modifying Aβ antibody for early AD. Secondary prevention trials with Aβ antibodies are underway.
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October 2024
Departments of Dermatology, and.
Background: Prior studies describe wide local excision and "slow Mohs" outcomes for periocular melanoma. Mohs micrographic surgery (MMS) with immunohistochemistry maximizes tissue preservation and offers same-day comprehensive margin evaluation, which facilitates expedited repair, and coordination of oculoplastic reconstruction when necessary.
Objective: To describe oncologic and reconstructive outcomes of invasive periocular cutaneous melanoma treated with immunohistochemistry-assisted MMS.
Cureus
August 2024
Dermatology, Carol Davila University of Medicine and Pharmacy, Elias Emergency University Hospital, Bucharest, ROU.
Cureus
August 2024
Dermatology, River Ridge Dermatology, Blacksburg, USA.
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