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Prematurity-related chronic respiratory disease across the life course.
Eur Respir J
June 2023
Department of Pediatrics, Division of Respiratory Medicine and Allergology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
Development of a severity scale to assess chronic lung disease after extremely preterm birth.
Pediatr Pulmonol
June 2021
Global Evidence and Outcomes, Takeda, Lexington, Massachusetts, USA.
Objective: Chronic lung disease of prematurity (CLDP) is a frequent complication of prematurity. We aimed to identify what clinicians believe are the most important factors determining the severity of CLDP in extremely preterm infants (<28 weeks gestational age) after discharge from the neonatal intensive care unit (NICU) through 12 months corrected age (CA), and to evaluate how these factors should be weighted for scoring, to develop a CLDP severity scale.
Study Design: Clinicians completed a three-round online survey utilizing Delphi methodology.
Premature or Small for Gestational Age Discrimination: International Multicenter Trial Protocol for Classification of the Low-Birth-Weight Newborn Through the Optical Properties of the Skin.
JMIR Res Protoc
July 2020
Faculty of Medicine, Universidade Federal de Minas Gerais, Brazil, Belo Horizonte, Brazil.
Background: A low birth weight is an independent risk factor for adverse infant outcomes and a predictor of chronic disease in adulthood. In these situations, differentiating between prematurity and small for gestational age (SGA) or simultaneous conditions is essential to ensuring adequate care. Such diagnoses, however, depend on reliable pregnancy dating, which can be challenging in developing countries.
View Article and Find Full Text PDFOutcomes of preterm infants conceived with in vitro fertilization.
J Perinatol
May 2019
The Center for Research, Education, Quality and Safety, MEDNAX National Medical Group, Sunrise, FL, USA.
Objectives: To determine if there is increased risk of prematurity-related complications for in vitro fertilization (IVF)-conceived preterm infants compared to matched controls.
Study Design: Cohort study of 23-34 weeks' preterm infants from 329 US NICUs discharged from 2009 to 2016. Each IVF patient was matched to three controls.
Neonatal brain injury causes cerebellar learning deficits and Purkinje cell dysfunction.
Nat Commun
August 2018
Center for Neuroscience Research, Children's Research Institute, Children's National Medical Center, Washington, DC, USA.
Premature infants are more likely to develop locomotor disorders than term infants. In a chronic sub-lethal hypoxia (Hx) mouse model of neonatal brain injury, we recently demonstrated the presence of cellular and physiological changes in the cerebellar white matter. We also observed Hx-induced delay in Purkinje cell (PC) arborization.
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