Reported herein is the development of a novel method for the activation of thioglycosides and thioimidates using benzyl trichloroacetimidate in the presence of catalytic triflic acid. Excellent yields have been achieved with reactive substrates, whereas efficiency of reactions with unreactive glycosyl donors and/or acceptors was modest.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528260 | PMC |
| http://dx.doi.org/10.1016/j.carres.2023.108872 | DOI Listing |
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