AI Article Synopsis

  • The study aimed to investigate the radial peripapillary capillaris (RPC) and intra-papillary capillaris (IPC) in patients with acute retinal necrosis (ARN) using optical coherence tomography angiography (OCTA).
  • Thirteen patients were analyzed, and while 12 showed no visual abnormalities through standard eye exams, OCTA revealed significant issues: 69% had RPC morphological abnormalities, and 62% showed a decrease in capillary networks.
  • The findings indicate that even in cases of ARN that appear mild and have good visual outcomes, there are underlying impairments in the capillaries, suggesting possible optic nerve damage.

Article Abstract

Purpose: To analyze radial peripapillary capillaris (RPC) and intra-papillary capillaris (IPC) using optical coherence tomography angiography (OCTA) in acute retinal necrosis (ARN) with good outcome.

Methods: RPC and IPC were analyzed by OCTA in patients diagnosed with ARN and treated with pharmacotherapy alone without surgery at the Tokyo Medical University Hospital.

Results: A total of 13 patients were studied. Ophthalmoscopic examination showed no abnormality in the optic disc in 12 of the 13 patients. However, OCTA findings of the affected eye compared with the unaffected fellow eye revealed morphological abnormalities in RPC in nine cases (69%) and decrease in capillary network in RPC or IPC in eight cases (62%).

Conclusion: In ARN, RPC and IPC were impaired even in eyes that were healed with medical treatment only without requiring surgical intervention and had no abnormal findings on ophthalmoscopic examination. This result suggests the presence of some degrees of optic neuropathy even in mild cases with good visual prognosis.

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Source
http://dx.doi.org/10.1080/09273948.2023.2221741DOI Listing

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