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Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, , and mice'. | LitMetric

AI Article Synopsis

  • A recent study by Abrams et al. claims that a simple dietary supplement can lead to appendage regeneration in jellyfish, fruit flies, and mice, which challenges prior beliefs about the regeneration abilities of these species.
  • In contrast, our replication of these experiments found no evidence of leg regeneration in fruit flies or mice.
  • We further analyzed the "white blob" seen at the amputation site in Abrams et al.'s work and determined it is actually composed of bacteria, rather than regenerated tissue.

Article Abstract

Abrams et al. report that a simple dietary supplement is sufficient to induce appendage regeneration in jellyfish, fruit flies, and mice (Abrams et al., 2021). This conclusion is surprising because it was previously thought that flies and mice lack the capacity for regeneration after injury. We replicated the experiments of Abrams et al. but did not observe any instances of leg regeneration. We also conclude that the "white blob" observed at the amputation site by Abrams et al. consists of bacteria and is not regenerated tissue.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287152PMC
http://dx.doi.org/10.7554/eLife.84435DOI Listing

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