An experimental study to evaluate (combination of properties).

Ayu

Department of Pharmacology, ITRA, Jamnagar, Gujarat, India.

Published: May 2023

Introduction: implies the combination or admixture of different (properties) in a (substance). Every in this world is composed of different varying in their quantity and potency. The final resultant action of the depends on the combination of and their interaction with each other.

Aim: The present study was aimed to explain the manifestation of (action) of a through its (properties) and to evaluate the effect of the combination of (cool property) with different other on digestion and metabolism in an animal model.

Materials And Methods: The test drugs ( Linn.) and ( Linn.) were dried and powdered. A total of 18 adult healthy male and female Wistar strain albino rats were grouped randomly into three groups out of which the first was the control group and administered with distilled water. The second and third groups were fed with powder of and , respectively, in the suspended form in distilled water. Test drugs were administered daily for 12 consecutive days. During the experimental phase, relative food intake, relative water intake, relative urine output, relative stool output, and food conversion ratio were recorded on the 3, 6, 9, and 12 day among which the 3 day was considered as the initial day for the assessment, whereas body weight was measured from the 1 day of the study. Throughout the study, the main focus was on how these parameters change in and -treated rats which are having different combinations of with reference to the control group.

Results: Both and groups showed a nonsignificant increase in relative food and water intake, nonsignificant increase in relative urine output, significant decrease in relative stool output, and significant increase in food conversion ratio. Body weight was nonsignificantly increased in group, whereas it was nonsignificantly decreased in group. This study aimed to show how the are interacting and resulting in either by dominating or suppressing or giving a combined effect of . This study provides initial data regarding the concept of (combination of properties).

Conclusion: The study concludes that all the in a interact and exhibit their resultant action, i.e., based on , with emphasis on example of assessment of the effects of , namely, and on physiological parameters (digestion and metabolism) have been assessed experimentally in animal models to evaluation of the combination of .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281246PMC
http://dx.doi.org/10.4103/ayu.ayu_229_21DOI Listing

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