More than 111 patients with traumatic diaphragmatic hernia (TDH) were treated in a 5 1/2-year period; eight (7.2%) were first recognized more than 30 days postinjury. All were men, and their average age was 33.4 years. Seven injuries were on the left side; one was on the right side. The mechanism of injury was equally divided between penetrating and blunt trauma. Chest roentgenographic abnormalities were seen in all patients. Visceral reduction and diaphragmatic repair, despite strangulation in four patients, was accomplished without mortality and with minimal morbidity. Delayed presentation of TDH is reviewed, emphasizing diagnostic features encountered in the emergency department (ED).
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http://dx.doi.org/10.1016/0736-4679(86)90106-x | DOI Listing |
Introduction: Children and adolescents with neurodevelopmental and psychiatric comorbidities, particularly autism spectrum disorder and developmental delays (ASD/DD), present unique challenges in pediatric emergency department (PED) settings. Youths with ASD/DD are prone to sensory overload and frequently exhibit agitation and/or aggression, necessitating specialized interventions. However, PEDs lack standardized protocols for managing behavioral dysregulation in this vulnerable population, often relying on anecdotal treatment approaches that hinder the provision of safe, effective and individualized care.
View Article and Find Full Text PDFVaccines (Basel)
December 2024
Research Institute for Biological Safety Problems, Gvardeiskiy 080409, Kazakhstan.
The research conducted in this preclinical study assesses QazCovid-live, a live attenuated COVID-19 vaccine created in Kazakhstan, by conducting preclinical evaluations of safety, immunogenicity, and allergenicity in various animal models, including mice, rats, hamsters, and guinea pigs. The vaccine, developed by attenuating SARS-CoV-2 via numerous Vero cell passages, had no significant adverse effects in acute and subacute toxicity assessments, even at elevated dosages. Allergenicity testing indicated the absence of both immediate and delayed hypersensitivity reactions.
View Article and Find Full Text PDFVaccines (Basel)
November 2024
Asia-Pacific Immunization Coalition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
The recent resurgence of mpox highlights the urgent need for rethinking vaccination strategies globally, underscored by the painful memories of past public health crises where delayed responses and inequitable vaccine distribution exacerbated the spread of infectious diseases. The inaugural APIC-ADVA Asia Pacific Summit on Infectious Diseases and Immunization, themed "Vaccination for All: Access, Confidence and Equity (ACE)", was held in Singapore from 31 October to 1 November 2023 in an attempt to present best practices and hard-won insights from battling COVID-19 and other pandemics in the Asia-Pacific region. This summit was co-convened by the Asia-Pacific Immunization Coalition (APIC) and Asia Dengue Voice and Action (ADVA).
View Article and Find Full Text PDFSensors (Basel)
December 2024
Antal Bejczy Center for Intelligent Robotics, Obuda University, 1034 Budapest, Hungary.
This paper presents a robust and efficient method for validating the accuracy of orientation sensors commonly used in practical applications, leveraging measurements from a commercial robotic manipulator as a high-precision reference. The key concept lies in determining the rotational transformations between the robot's base frame and the sensor's reference, as well as between the TCP (Tool Center Point) frame and the sensor frame, without requiring precise alignment. Key advantages of the proposed method include its independence from the exact measurement of rotations between the reference instrumentation and the sensor, systematic testing capabilities, and the ability to produce repeatable excitation patterns under controlled conditions.
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December 2024
Faculty of Mechanical Engineering, Lublin University of Technology, 36 Nadbystrzycka St., 20-618 Lublin, Poland.
This article presents a laboratory device by which the course of two signals can be detected using two types of sensors-strain gauges and the DEWESoft DS-NET measuring apparatus. The values of the coefficient of friction of the brake lining when moving against the rotating shell of the brake drum were determined from the physical quantities sensed by tensometric sensors and transformed into electrical quantities. The friction coefficient of the brake lining on the circumference of the rotating brake disc shell can be calculated from the known values measured by the sensors, the design dimensions of the brake, and the revolutions of the rotating parts system.
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