Analog optical and electronic hardware has emerged as a promising alternative to digital electronics to improve the efficiency of deep neural networks (DNNs). However, previous work has been limited in scalability (input vector length ≈ 100 elements) or has required nonstandard DNN models and retraining, hindering widespread adoption. Here, we present an analog, CMOS-compatible DNN processor that uses free-space optics to reconfigurably distribute an input vector and optoelectronics for static, updatable weighting and the nonlinearity-with ≈ 1000 and beyond. We demonstrate single-shot-per-layer classification of the MNIST, Fashion-MNIST, and QuickDraw datasets with standard fully connected DNNs, achieving respective accuracies of 95.6, 83.3, and 79.0% without preprocessing or retraining. We also experimentally determine the fundamental upper bound on throughput (∼0.9 exaMAC/s), set by the maximum optical bandwidth before substantial increase in error. Our combination of wide spectral and spatial bandwidths enables highly efficient computing for next-generation DNNs.
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http://dx.doi.org/10.1126/sciadv.adg7904 | DOI Listing |
BMC Bioinformatics
January 2025
Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital of Capital Medical University, Beijing, 101100, China.
Background: MicroRNAs (miRNAs) are pivotal in the initiation and progression of complex human diseases and have been identified as targets for small molecule (SM) drugs. However, the expensive and time-intensive characteristics of conventional experimental techniques for identifying SM-miRNA associations highlight the necessity for efficient computational methodologies in this field.
Results: In this study, we proposed a deep learning method called Multi-source Data Fusion and Graph Neural Networks for Small Molecule-MiRNA Association (MDFGNN-SMMA) to predict potential SM-miRNA associations.
Heliyon
January 2025
Department of Earth Sciences, Carleton University, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada.
Metal mining operations can release toxic metals to surrounding environments where site-specific conditions control the movement of contaminants. Colloid-facilitated transport, the transport of contaminants with small, mobile particles, has been recognized as a potential contaminant transport vector in groundwater, but it remains unclear under what conditions it is important and whether neutral, metal-rich mine drainage from legacy mining impacts this transport vector. This work presents a set of laboratory column experiments that study the effect of colloids on metal mobility in saturated, wetland sediment that has been receiving neutral mine drainage for nearly a century, using mixed and single metal input solutions at neutral pH.
View Article and Find Full Text PDFJ Biomech
January 2025
Sport and Physical Activity Research Centre, Sheffield Hallam University, Olympic Legacy Park, 2 Old Hall Rd, Sheffield S9 3TY, United Kingdom. Electronic address:
Changes to the variability within biomechanical signals may reflect a change in the health of the human system. However, for running gait variability measures calculated from wearable device data, it is unknown whether a between-day difference reflects a shift in system dynamics reflective of a change in human health or is a result of poor between-day reliability of the measurement device or the biomechanical signal. This study investigated the reliability of stride time and sacral acceleration variability measures calculated from inertial measurement units (IMUs).
View Article and Find Full Text PDFNeural Netw
January 2025
School of Computer Science and Technology, East China Normal University, 200062, Shanghai, China.
Real-world image super-resolution (RISR) has received increased focus for improving the quality of SR images under unknown complex degradation. Existing methods rely on the heavy SR models to enhance low-resolution (LR) images of different degradation levels, which significantly restricts their practical deployments on resource-limited devices. In this paper, we propose a novel Dynamic Channel Splitting scheme for efficient Real-world Image Super-Resolution, termed DCS-RISR.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Departamento de Geografía, Facultad de Ciencias, Universidad de la República, Montevideo 4225, Uruguay.
Recent advancements in Earth Observation sensors, improved accessibility to imagery and the development of corresponding processing tools have significantly empowered researchers to extract insights from Multisource Remote Sensing. This study aims to use these technologies for mapping summer and winter Land Use/Land Cover features in Cuenca de la Laguna Merín, Uruguay, while comparing the performance of Random Forests, Support Vector Machines, and Gradient-Boosting Tree classifiers. The materials include Sentinel-2, Sentinel-1 and Shuttle Radar Topography Mission imagery, Google Earth Engine, training and validation datasets and quoted classifiers.
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