The occurrence of intervertebral gas secondary to the vacuum phenomenon has been previously described and is thought to be pathognomonic of degenerative disk disease. The case reported here illustrates that the intervertebral vacuum phenomenon may occur following trauma, suggesting that it is not exclusive to degenerative disk disease.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/00004728-198607000-00038 | DOI Listing |
Cell Biochem Biophys
January 2025
Department of Orthopedic, Wuhan Hospital of Traditional Chinese Medicine, Wuhan, 430014, Hubei Province, China.
Intervertebral disc degeneration (IDD) is the main pathological factor resulting in low back pain (LBP), the leading cause of disability globally. Inflammatory response and extracellular matrix (ECM) degradation are critical pathological features in the development of IDD. Gastrodin (GAS), a phenol compound isolated from Gastrodia elata Blume, plays an anti-inflammatory role in experimental models of multiple human diseases.
View Article and Find Full Text PDFInfect Drug Resist
November 2024
Chengdu University of Traditional Chinese Medicine Third Clinical Medical College/Affiliated Third Hospital, Pidu District Traditional Chinese Medicine Hospital, Chengdu, Sichuan, 611730, People's Republic of China.
(MC) is an aerobic Gram-negative cocci known to cause respiratory tract infections in humans as an opportunistic pathogen, with infections in other body parts being rare. This case involves an elderly female patient with a medical history of hypertension, type 2 diabetes, coronary heart disease, and osteoporosis. Following coronary angiography and lumbar spine surgery prompted by lower back and left lower limb pain, the patient developed persistent pus discharge from the lumbar spine wound post-surgery, which did not respond to conventional anti-infection therapy, leading to her transfer to our hospital.
View Article and Find Full Text PDFRadiol Case Rep
October 2024
Department of Radiology, Concord Repatriation and General Hospital, Sydney, Australia.
Intraosseous pneumatocysts are benign, gas-filled cystic structures of bone, typically asymptomatic and discovered incidentally on imaging. Their precise aetiology remains unclear, with the prevailing hypothesis being that they result from air accumulation within the bone due to a vacuum phenomenon, typically linked to an adjacent joint space or intervertebral disc. We report the case of a 37-year-old man with an incidental intraosseous pneumatocyst of the scapula, which was evaluated with CT and MRI.
View Article and Find Full Text PDFBiomaterials
February 2025
Department of Spine Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, No.160 Pujian Road, Shanghai, 200127, PR China. Electronic address:
Currently, mitochondrial dysfunction caused by oxidative stress is a growing concern in degenerative diseases, notably intervertebral disc degeneration (IVDD). Dysregulation of the balance of mitochondrial quality control (MQC) has been considered the key contributor, while it's still challenging to effectively harmonize different MQC components in a simple and biologically safe way. Hydrogen gas (H) is a promising mitochondrial therapeutic molecule due to its bio-reductivity and diffusibility across cellular membranes, yet its relationship with MQC regulation remains unknown.
View Article and Find Full Text PDFJ Orthop Translat
May 2024
Department of Spine Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250000, China.
Backgroud: Iron overload is a prevalent condition in the elderly, often associated with various degenerative diseases, including intervertebral disc degeneration (IDD). Nevertheless, the mechanisms responsible for iron ion accumulation in tissues and the mechanism that regulate iron homeostasis remain unclear. Transferrin receptor-1 (TFR1) serves as the primary cellular iron gate, playing a pivotal role in controlling intracellular iron levels, however its involvement in IDD pathogenesis and the underlying mechanism remains obscure.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!