AI Article Synopsis

  • The study aimed to explore how exercise might decrease the likelihood of COVID-19 infection among unvaccinated individuals who had close contact with infected people.
  • It analyzed data from 5,338 contact persons, comparing those who tested positive for COVID-19 (CP-P) with those who remained negative (CP-N), focusing on their physical activity and lifestyle prior to the pandemic.
  • Findings indicated that individuals who stayed active were less likely to contract the virus, suggesting that promoting a physically active lifestyle could help reduce infection rates in future pandemics, particularly for those who are sedentary or have chronic health issues.

Article Abstract

Objectives: To investigate the potential protective role of exercise on the odds of COVID-19 infection in unvaccinated contact persons (CPs) who were at higher risk of infection due to confirmed contact with infected persons.

Methods: Before the onset of the vaccination campaign, the first wave of the CoCo-Fakt online survey was conducted with SARS-CoV-2-positive persons and their confirmed contacts who were isolated/quarantined between 1 March 2020 and 9 December 2020. Within this analysis, 5338 CPs were included and divided into those who subsequently tested positive (CP-P) and those who remained negative (CP-N). We assessed demographics as well as pre-pandemic lifestyle characteristics including physical activity (PA; type, frequency, time, intensity; duration clustered as 'below PA guidelines', 'meeting PA guidelines', and 'above PA guidelines'; intensity clustered as 'low intensity' and 'moderate-to-vigorous intensity') and sedentary behaviour.

Results: A greater percentage of CP-Ns reported being active before the pandemic compared to CP-Ps (69% vs. 63%; p = .004). Moreover, CP-Ns reported higher PA duration (164.1 min/week vs. 143.2 min/week; p = .038) and higher PA intensities than CP-Ps (67% vs. 60% moderate-to-vigorous intensity, 33% vs. 40% low intensity; p = .003). Adjusting for age, sex, socioeconomic status, migration background, and pre-existing chronic diseases, the odds of infection were negatively associated with exercise (yes/no) (Nagelkerke R = 1.9%), PA levels above PA guidelines (Nagelkerke R = 2.0%), and PA intensity (Nagelkerke R = 1.8%).

Conclusion: Due to the beneficial effects of PA on the odds of infection, an active lifestyle should be promoted especially during possible subsequent pandemics (while taking into account necessary hygiene measures). Moreover, inactive and chronically ill persons should be especially encouraged to adopt a healthier lifestyle.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284734PMC
http://dx.doi.org/10.1186/s40798-023-00592-6DOI Listing

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