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Comprehensive Insights into Monkeypox (mpox): Recent Advances in Epidemiology, Diagnostic Approaches and Therapeutic Strategies.
Pathogens
December 2024
Center for General Education, National Chung Hsing University, Taichung 402, Taiwan.
Monkeypox (mpox) is a viral infection closely related to smallpox, manifesting as a milder febrile rash in affected individuals. Over the past two decades, the incidence of mpox has surged, possibly linked to a declining immunity against the smallpox vaccine worldwide. Recent outbreaks of mpox in multiple countries have sparked concerns regarding altered transmission patterns and the potential for a global menace.
View Article and Find Full Text PDFDynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors.
Sci Rep
January 2025
Department of Mathematics and Statistics, College of Science, Taif University, P.O. Box 11099, 21944, Taif, Saudi Arabia.
The monkeypox virus (MPXV), which is a member of the Orthopoxvirus genus in the class Poxviridae, is the causative agent of the zoonotic viral infection MPXV. The disease is similar to smallpox, but it is usually less dangerous. This study examines the evolution of the MPXV epidemic in Canada with an emphasis on the effects of control employing actual data.
View Article and Find Full Text PDFImpact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities.
Int J Infect Dis
January 2025
Department of Epidemiology and Biostatistics, McGill University, Montréal, QC, Canada. Electronic address:
Objectives: The global mpox (clade II) outbreak of 2022 primarily affected gay, bisexual, and other men who have sex with men (GBM) and was met with swift community and public health responses. We aimed to estimate the relative impact of changes in sexual behaviours, contact tracing/isolation, and first-dose vaccination on transmission in Canadian cities.
Methods: We estimated changes in sexual behaviours during the outbreak using 2022 data from the Engage Cohort Study which recruited self-identified GBM in Montréal, Toronto, and Vancouver (n=1,445).
Mpox and the men who have sex with men (MSM) community in Nigeria: Exploratory insights from MSM and persons providing healthcare services to them.
Glob Public Health
December 2025
Health & Nutrition Cluster, Institute of Development Studies, University of Sussex, Brighton, United Kingdom.
The current mpox outbreak has challenged previous understanding of the disease, with human-to-human transmission being a significant mode of transmission, particularly among gay, bisexual, and other men who have sex with men (GBMSM). A knowledge gap exists on MSM's mpox experiences in Nigeria's restrictive sociolegal context. This study explored mpox awareness, knowledge, and experiences among MSM in Lagos, Nigeria, through 28 in-depth interviews.
View Article and Find Full Text PDFImmunobiology of MPox Infection and Its Management: Experience From Developing Nations.
Rev Med Virol
January 2025
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Purpose: As humanity grapples with the COVID-19 pandemic caused by the novel SARS-CoV-2 virus, the rising threats of the MPox virus (MPXV) in 2022 and 2024 have shown signs of global transmission and the potential to spark another pandemic. Though MPXV has been present for over 5 decades, with cases traditionally confined to endemic regions in West and Central Africa, recent outbreaks have occurred in multiple non-endemic regions, declaring itself as a Public Health Emergency of International Concern. This study aims to examine the patterns of MPXV transmission, its zoonotic potential, associated complications, and viable strategies to control its spread.
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