Serum uromodulin levels are higher in healthy female participants than healthy male participants. Serum uromodulin levels in participants with normal kidney function do not correlate with eGFR but do correlate with body mass index. Estrogen increases uromodulin production, likely because of noncanonical and half estrogen response elements in the gene.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547224PMC
http://dx.doi.org/10.34067/KID.0000000000000197DOI Listing

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