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Antenatal Diagnosis and Treatment in Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency and Congenital Adrenal Hyperplasia Screening in Newborns.
J Clin Res Pediatr Endocrinol
December 2024
Department of Pediatric Endocrinology, Marmara University, School of Medicine, Istanbul, Turkiye.
Signs of virilization, such as clitoromegaly, labio-scrotal fusion, and urogenital sinus may be observed in females with 21-hydroxylase deficiency (21-OHD) and other rare virilizing forms of congenital adrenal hyperplasia (CAH). This makes sex determination difficult, and multiple reconstructive surgeries in the postnatal period may be required. As 21-OHD is an autosomal recessive disease, the chance of any child being affected is one in four and so only one in eight will be an affected female.
View Article and Find Full Text PDFHusband's Contributions to Stimulate Wife's Confidence Experiencing Role Transition: Cross-Sectional Study.
SAGE Open Nurs
December 2024
Faculty of Nursing, Universitas Airlangga, Surabaya, Indonesia.
Introduction: Pregnancy can cause various physical and physiological changes. It affects confidence, resulting in depression and disturbing health not only for a mother but also for her fetus. These will also determine the ability of the mother to take care of her baby after delivery.
View Article and Find Full Text PDFTubular single-port endoscope-assisted surgery for fetal myelomeningocele repair.
J Neurosurg Pediatr
December 2024
2Fetal Medicine Division, Hospital e Maternidade Santa Joana, São Paulo; and.
Objective: The authors aimed to describe a low-cost and easily reproducible alteration of the Bruner and Tulipan procedure to preserve uterine muscular fibers. They conducted a retrospective cohort study of 10 pregnant women whose fetuses developed lumbosacral myelomeningocele (MM). The MM was repaired through a fetal neurosurgical procedure using a tubular single-port endoscope-assisted technique.
View Article and Find Full Text PDFPrenatal Origins of Obstructive Airway Disease: Starting on the Wrong Trajectory?
Compr Physiol
December 2024
School of Human Sciences, The University of Western Australia, Crawley, Western Australia, Australia.
From the results of well-performed population health studies, we now have excellent data demonstrating that deficits in adult lung function may be present early in life, possibly as a result of developmental disorders, incurring a lifelong risk of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease. Suboptimal fetal development results in intrauterine growth restriction and low birth weight at term (an outcome distinct from preterm complications), which are associated with subsequent obstructive disease. Numerous prenatal exposures and disorders compromise fetal development and these are summarized herein.
View Article and Find Full Text PDFNovel neural network classification of maternal fetal ultrasound planes through optimized feature selection.
BMC Med Imaging
December 2024
Chennai Institute of Technology, Chennai, India.
Ultrasound (US) imaging is an essential diagnostic technique in prenatal care, enabling enhanced surveillance of fetal growth and development. Fetal ultrasonography standard planes are crucial for evaluating fetal development parameters and detecting abnormalities. Real-time imaging, low cost, non-invasiveness, and accessibility make US imaging indispensable in clinical practice.
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