Object detection has been widely applied in various fields with the rapid development of deep learning in recent years. However, detecting small objects is still a challenging task because of the limited information in features and the complex background. To further enhance the detection accuracy of small objects, this paper proposes an efficient single-shot detector with weight-based feature fusion (WFFA-SSD). First, a weight-based feature fusion block is designed to adaptively fuse information from several multi-scale feature maps. The feature fusion block can exploit contextual information for feature maps with large resolutions. Then, a context attention block is applied to reinforce the local region in the feature maps. Moreover, a pyramids aggregation block is applied to combine the two feature pyramids to classify and locate target objects. The experimental results demonstrate that the proposed WFFA-SSD achieves higher mean Average Precision (mAP) under the premise of ensuring real-time performance. WFFA-SSD increases the mAP of the car by 4.12% on the test set of the CARPK.
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http://dx.doi.org/10.1038/s41598-023-36972-x | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Neurotransmitter release is triggered in microseconds by Ca-binding to the Synaptotagmin-1 C-domains and by SNARE complexes that form four-helix bundles between synaptic vesicles and plasma membranes, but the coupling mechanism between Ca-sensing and membrane fusion is unknown. Release requires extension of SNARE helices into juxtamembrane linkers that precede transmembrane regions (linker zippering) and binding of the Synaptotagmin-1 CB domain to SNARE complexes through a "primary interface" comprising two regions (I and II). The Synaptotagmin-1 Ca-binding loops were believed to accelerate membrane fusion by inducing membrane curvature, perturbing lipid bilayers, or helping bridge the membranes, but SNARE complex binding through the primary interface orients the Ca-binding loops away from the fusion site, hindering these putative activities.
View Article and Find Full Text PDFMagn Reson Imaging
January 2025
Background: Huai-he Hospital of Henan University, Kaifeng, China. Electronic address:
Objective: To explore the application value of MRI-based imaging histology and deep learning model in the identification and classification of breast phyllodes tumors.
Methods: Seventy-seven patients diagnosed as breast phyllodes tumors and fibroadenomas by pathological examination were retrospectively analyzed, and traditional radiomics features, subregion radiomics features, and deep learning features were extracted from MRI images, respectively. The features were screened and modeled using variance selection method, statistical test, random forest importance ranking method, Spearman correlation analysis, least absolute shrinkage and selection operator (LASSO).
Food Chem
January 2025
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, PR China; Key Laboratory of Biology and Cultivation of Herb Medicine, Ministry of Agriculture and Rural Affairs, Beijing 100700, PR China. Electronic address:
Ensuring food traceability is essential for maintaining safety and authenticity. Angelica sinensis (Oliv.) Diels (AS), a medicinal food prized for its rich nutritional value and tonic effects, is frequently vulnerable to geographic origin fraud.
View Article and Find Full Text PDFInt J Cardiovasc Imaging
January 2025
Shanxi Cardiovascular Hospital, 18 Yifen Street, Taiyuan, 030024, Shanxi, China.
Amid an aging global population, heart failure has become a leading cause of hospitalization among older people. Its high prevalence and mortality rates underscore the importance of accurate mortality prediction for swift disease progression assessment and better patient outcomes. The evolution of artificial intelligence (AI) presents new avenues for predicting heart failure mortality.
View Article and Find Full Text PDFPediatr Dev Pathol
January 2025
Lauren V. Ackerman Laboratory of Surgical Pathology, Washington University Medical Center, St. Louis, MO, USA.
A desmoplastic small round cell tumor (DSRCT) presented in a 13-year-old female with an acute abdomen due to torsion of a fallopian tube cyst. She was found to have an incidental 2 cm pedunculated, solid, and multicystic mass attached to the pelvic floor on laparoscopy. The neoplasm had a variably myxoid and spindle cell pattern with nests and cords of small cells, forming pseudocysts, and true cysts lined by ciliated epithelium which were PAX-8+ and ER+/PR+.
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