AI Article Synopsis
- - Chitosan microparticles are effective for encapsulating ingredients due to their favorable properties like being pH-responsive, biocompatible, and antimicrobial.
- - The study describes the creation of chitosan-phytate (CS-PA) microparticles with different shapes using gas-shearing microfluidics, where particle size can be adjusted by changing gas flow rates and ingredient concentrations.
- - These CS-PA microparticles show excellent stability and performance, making them promising carriers for active ingredients in pharmaceuticals, food, and cosmetics.
Article Abstract
Chitosan microparticles are frequently used for the encapsulation of ingredients, owing to their pH-responsive, renewable, biocompatible and antimicrobial properties. Herein, pH-responsive antibacterial encapsulation carriers in chitosan-phytate (CS-PA) microparticles with various morphologies were prepared by gas-shearing microfluidics. Microparticles sizes were tuned by gas flow rate in production, and the CS and PA concentration significantly dominated the morphology of microparticles. Additionally, microparticles exhibit great storage stability, lyophilizing rehydration performance, pH-responsive behavior, as well as antibacterial and biocompatible effect, indicating that CS-PA microparticles are expected to become an ideal carrier for the actives encapsulation in pharmaceutical, food and cosmetic industries.
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| http://dx.doi.org/10.1016/j.jcis.2023.06.006 | DOI Listing |
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