We are honored to present this special issue of the Environmental Science and Pollution Research which comprises the selected papers presented at the international conference on Advanced Materials for Photonics, Sensing and Energy Conversion Energy Applications, held in Marrakech, Morocco.
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| http://dx.doi.org/10.1007/s11356-023-27991-2 | DOI Listing |
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Prognostic and clinical heterogeneity of PD1 and PD-L1- immunohistochemical scores in endometrial cancers.
Arch Gynecol Obstet
January 2025
Department of Gynecology and Obstetrics, University Medical Center Schleswig-Holstein, Campus-Lübeck, Lübeck, Germany.
Introduction: PD1/PD-L1 inhibition (ICi) has recently become a new standard of care for patients with advanced MMR-deficient (MMRd) endometrial cancers. Nevertheless, response to immunotherapy is more complex than the presence of a single biomarker and therefore it remains challenging to predict patients response to ICi beyond MMRd tumors. Elevated PD-L1 expression (CPS ≥ 1) is often used as a prognostic marker as well as a predictive biomarker of response to ICi in different tumor types.
View Article and Find Full Text PDFTracking nonlinear conversion of light in van der Waals waveguides.
Nat Nanotechnol
January 2025
Center for Quantum Physics, Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement (MOE), School of Physics, Beijing Institute of Technology, Beijing, China.
The fate and mobility of chromium, arsenic and zinc in municipal sewage sludge during the co-pyrolysis process with organic and inorganic chlorides.
Sci Rep
January 2025
Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran.
Co-pyrolysis is an efficient approach for municipal sewage sludge (SS) treatment, facilitating the production of biochar and promoting the stabilization and removal of heavy metals, particularly when combined with chlorinated materials. This study explores the impact of pyrolysis temperatures (400 °C and 600 °C) and chlorinated additives (polyvinyl chloride (PVC) as an organic chloride source and ferric chloride (FeCl) as an inorganic chloride source) at 10% and 20% concentrations, on the yield, chemical speciation, leachability, and ecological risks of arsenic (As), chromium (Cr), and zinc (Zn) in biochar derived from SS. The results revealed that increasing the pyrolysis temperature from 400 to 600 °C significantly reduced biochar yield due to enhanced volatilization of organic components, as well as the removal of heavy metals in interaction with chlorinated materials.
View Article and Find Full Text PDFLectin-Mediated Labeling of Alkaline Phosphatase for Enzymatic Silver Deposition-Based Electrochemical Detection of Glycoprotein Tumor Markers.
Anal Chem
January 2025
Center for Advanced Analytical Science, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Sensing Materials and Devices, School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, P. R. China.
The screening of glycoprotein markers has become an integral part of the in vitro diagnosis of malignant tumors. Herein, an electrochemical method based on alkaline phosphatase (ALP)-mediated enzymatic silver deposition is reported for the highly sensitive detection of glycoprotein tumor markers, in which ALP enzymes are decorated to the glycan moieties of targets via the lectin-carbohydrate interactions. As glycoproteins are conjugated with multiple glycan chains, lectin-mediated labeling can result in the decoration of each target with multiple ALP enzymes.
View Article and Find Full Text PDFAdvanced Automated Model for Robust Bone Marrow Segmentation in Whole-body MRI.
Acad Radiol
January 2025
Division of Radiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany (F.B., M.G., H.P.S., S.D.); Diagnostic and Interventional Radiology, University Hospital Heidelberg, 69120 Heidelberg, Germany (T.F.W., M.W.).
Rationale And Objectives: To establish an advanced automated bone marrow (BM) segmentation model on whole-body (WB-)MRI in monoclonal plasma cell disorders (MPCD), and to demonstrate its robust performance on multicenter datasets with severe myeloma-related pathologies.
Materials And Methods: The study cohort comprised multi-vendor, multi-protocol imaging data acquired with varying field strength across 8 different centers. In total, 210 WB-MRIs of 207 MPCD patients were included.
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