A C(sp)-C(sp) reaction between aromatic hydrazines and quinoxalines has been developed through a photocatalytic system. The protocol is established for C(sp)-N bond cleavage and direct C(sp)-H functionalization for the coupling of C(sp)-C(sp) photocatalysis under mild and ideal air conditions without the presence of a strong base and metal. The mechanistic studies reveal that the generation of a benzene radical the oxidative cleavage of aromatic hydrazines for the cross-coupling of C(sp)-C(sp) with the assistance of a photocatalyst is essential. The process exhibits excellent compatibility with functional groups and provides convenient access to various 3-arylquinoxalin-2(1)-ones in good to excellent yields.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274563 | PMC |
| http://dx.doi.org/10.1039/d3ra03479h | DOI Listing |
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