AI Article Synopsis

  • A thoracic aortic aneurysm (TAA) is a serious condition involving an abnormal widening of the thoracic aorta, which can lead to high morbidity and mortality, but open surgery provides effective management options.
  • The study involved a retrospective analysis of 234 patients who underwent elective open thoracic surgery for TAA at University Hospital Southampton from 2015 to 2019, revealing key demographics, surgical procedures, and their outcomes, including a 30-day mortality rate of 5.13%.
  • Factors influencing complications included gender, the type of surgery performed, and the size of the aorta, emphasizing the need for risk discussions with patients prior to surgery, while current surgical practices align with international guidelines.

Article Abstract

Background A thoracic aortic aneurysm (TAA) is a diseased expansion of the thoracic aorta. There is morbidity associated with a dilated aorta, as well as significant mortality. Open thoracic surgery is the fundamental management for proximal lesions, offering definitive treatment with excellent results. This study aimed to summarize preoperative data and operative outcomes of patients who underwent TAA repair at our institution. Methods Data were retrospectively collected from 234 patients that underwent elective open thoracic surgery at University Hospital Southampton for TAA disease, between 2015 and 2019. Demographics, clinical factors, surgical details, as well as outcome measures, were gathered. Results There were 166 males and 68 females, with an overall mean age of 66 years. The breakdown of operations comprised 105 aortic roots, 171 ascending aorta, 20 aortic arch, and 12 descending aorta cases. The mean follow-up was 370 days. 30-day mortality was 5.13%. Mortality was associated with female gender, aortic root surgery, and prosthetic valves. Mean aortic diameters at the time of surgery for the non-genetic aortopathy and genetic aortopathy groups were respectively 4.93cm and 4.63cm in the aortic root, 5.56cm and 4.88cm in the ascending aorta, 5.08cm and 3.87cm in the aortic arch, and 6.63cm and 5.50cm in the descending aorta. Conclusion Several factors are associated with complications and morbidity, which should be considered when discussing the risks of intervention with patients. There were no neuroprotective strategies that altered post-operative neurological function. Current practice in our unit fits in with current international guidance.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270669PMC
http://dx.doi.org/10.7759/cureus.39102DOI Listing

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