Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/apa.16879 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Improving cellular therapy operations through pre-harvest measurement of peripheral CD34-positive cell counts in allogeneic stem cell harvest.
Ther Apher Dial
February 2025
Division of Transfusion and Cell Therapy, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
Introduction: Previously, our institution measured peripheral blood CD34 cell counts both pre- and post-peripheral blood stem cell harvest (PBSCH), with both samples analyzed simultaneously post-PBSCH. Since 2021, we have measured pre-CD34 cell counts during PBSCH, adjusting the processed blood volume based on these results. We retrospectively evaluated how this change impacted cellular therapy.
View Article and Find Full Text PDFShorter donor leukocyte telomere length is associated with poor peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor.
J Formos Med Assoc
June 2024
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Background/purpose: Insufficient numbers of peripheral blood stem cells (PBSC) after granulocyte colony-stimulating factor (G-CSF) mobilization occurs in a significant proportion of PBSC collections, often from older age donors. Telomere length (TL) is often used as an indicator of an individual's biological age. This study aimed to investigate the relationship between donors' leukocyte TL and the outcome of G-CSF-induced PBSC mobilization in healthy unrelated donors.
View Article and Find Full Text PDFPre-harvest CD34 cell counts predicted peripheral blood stem cell collection yields.
Acta Paediatr
October 2023
TamCAM - Tampere Center for Child, Adolescent and Maternal Health Research, Faculty of Health Sciences and Medicine, Tampere University, Tampere, Finland.
Pattern of autologous stem cell transplants at a tertiary care government hospital, with emphasis on transplant outcomes with pre-harvest CD34+ level.
Blood Cell Ther
February 2022
Department of Haematology, Nil Ratan Sircar Medical College and Hospital, Kolkata, India.
Purpose: Autologous stem cell transplantation (ASCT) is an established therapy for many hematological diseases. This study assessed the pattern of ASCTs at a tertiary care center and associated factors, including pre-harvest CD34+ stem cell levels, leading to improved engraftment outcomes.
Methodology: A retrospective study was conducted in India, between February 2009-August 2020.
Correlation between peripheral blood automated hematopoietic progenitor cell counts and flow cytometric CD34 cell counts differs according to diagnosis in patients undergoing autologous peripheral blood stem cell transplantation.
J Clin Apher
October 2021
Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Background: An automated hematopoietic progenitor cell count measurement in Sysmex XN analyzer (XN-HPC) has been developed to assist flow cytometry CD34 cell count measurement, which requires technical expertise and a long turnaround time. Here, we evaluated the correlation between XN-HPC count and flow cytometric CD34 cell count in pre-harvest peripheral blood (PB) samples from patients undergoing autologous peripheral blood stem cell (PBSC) transplantation according to diagnosis and investigated the possible cause of the decreased correlation in plasma cell neoplasm patients.
Materials And Methods: We retrospectively included 399 patient data that had matched PB XN-HPC count and CD34 cell count of PB and apheresis product from Samsung Medical Center (SMC) and the Hematopoietic Stem Cell (HSC) registry.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!