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Seroprevalence of antibodies against SARS-CoV-2 in the Valencian Community (Spain) as of October 2022. | LitMetric

Seroprevalence of antibodies against SARS-CoV-2 in the Valencian Community (Spain) as of October 2022.

Gac Sanit

Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, València, Spain; CIBER de Enfermedades Infecciosas (CIBERINFEC), Spain; Department of Microbiology, School of Medicine, University of Valencia, València, Spain.

Published: June 2023

Objective: To estimate the seroprevalence of SARS-CoV-2 antibodies in the Valencian Community (Spain) in October 2022, when BA.5 was the predominant variant.

Method: Cross-sectional, region-wide, population-based serosurvey study in 88 randomly selected primary care centers of the Valencian Community.

Results: Seroprevalence of anti-nucleocapsid (indicative of past infection) and total receptor binding domain (indicative of past infection or vaccination) antibodies was 71.0% (confidence interval [CI]: 67.8-74.2) and 98.4% (CI: 97.5-99.3), respectively. 66.7% (CI: 63.4-70.0) of the population shows hybrid immunity, but only 43.2% in those 80 and over.

Conclusions: The high proportion of hybrid immunity detected is relevant for public health strategies. A second vaccination booster was advisable in the elderly population.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192597PMC
http://dx.doi.org/10.1016/j.gaceta.2023.102312DOI Listing

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