Objectives: Evaluation of Distortion Product Otoacoustic Emissions (DPOAEs) by combining Air Conduction (AC) and Bone Conduction (BC) stimuli in infants.
Methods: Measurements were performed in 19 normal hearing infants, and in 23 adults serving as a control group. The stimulus consisted either of two AC tones, or of combined AC/BC tones. DPOAEs were measured for f2 at 0.7, 1, 2, 4 kHz, and a constant ratio of f2/f1 = 1.22. Sound pressure level of the primary stimulus L1 was held constant at 70 dB SPL, while the level of L2 was decreased in 10 dB steps from 70 to 40 dB SPL. A response was included for further analysis when DPOAEs reached a Signal to Noise Ratio (SNR) of ≥6 dB. Additional DPOAE responses of <6 dB SNR were included when visual inspection of the measurements indicated clear DPOAEs.
Results: DPOAEs could be elicited in infants at 2 and 4 kHz for the AC/BC stimulus. DPOAE amplitudes evoked by the AC/AC stimulus were larger than those by the AC/BC stimulus, with the exception of 1 kHz. The highest amplitudes of DPOAEs were registered for a stimulation level of L1 = L2 = 70 dB, with the exception of AC/AC at 1 kHz, where the highest amplitudes were with L1-L2 = 10 dB.
Conclusions: We demonstrated that DPOAEs can be generated in infants by a combined AC/BC stimulus at 2 and 4 kHz. The high noise floor needs to be further reduced to achieve more valid measurements in frequencies <2 kHz.
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http://dx.doi.org/10.1016/j.ijporl.2023.111628 | DOI Listing |
Alzheimers Dement
December 2024
University of Ibadan, Ibadan, Oyo, Nigeria.
Background: The brain is a potential target for aluminium toxicity as it induces oxidative stress, strategies, rich in polyphenolic compound, containing flavonoid and possessing antioxidant property, found in natural plant products, to attenuate aluminium-induced impairments could provide a potential therapeutic intervention and protection for aluminium neurotoxicity.
Method: Forty adult rats weighing between 160 - 165g was used. The rats were divided into four groups (n = 10).
Nat Commun
January 2025
Department of Energy Conversion and Storage, Technical University of Denmark, Lyngby, Denmark.
Electrostriction is the upsurge of strain under an electric field in any dielectric material. Oxygen-defective metal oxides, such as acceptor-doped ceria, exhibit high electrostriction 10 mV values, which can be further enhanced via interface engineering at the nanoscale. This effect in ceria is "non-classical" as it arises from an intricate relation between defect-induced polarisation and local elastic distortion in the lattice.
View Article and Find Full Text PDFFront Public Health
January 2025
School of Economics, Anhui University of Finance and Economics, Bengbu, China.
Introduction: Information disclosure is important in promoting unsafe food recalls and reducing potential food safety risks. However, the governance of unsafe food recall information in China is distorted, leading to cognitive dissonance in Chinese consumers' perceptions of unsafe food recall information. Focusing on consumers' search and cognitive costs, this study suggests that market regulators should proactively and fully disclose unsafe food recall information to satisfy consumers' needs and preferences for recall information, thereby optimizing consumer perceptions and facilitating the improvement of the information governance system for unsafe food recalls.
View Article and Find Full Text PDFAdv Mater
January 2025
Hefei National Laboratory for Physical Sciences at the Microscale, Department of Applied Chemistry, Department of Environmental Science and Engineering, Center of Advanced Nanocatalysis (CAN), University of Science & Technology of China, Hefei, Anhui, 230026, P. R. China.
Substitution metal doping strategies are crucial for developing catalysts capable of activating O, but the leaching of metal dopants has greatly hindered their potential for extensive oxidation reactions under mild conditions. Here, the study develops an entropy-increase strategy to synthesize high-entropy metal (Mg, Ca, Mn, Fe, and Co) interstitial functionalized anatase TiO (HE-TiO) nanosheets, demonstrating remarkable degradation efficiency across a wide pH range and exceptional stability in a flow-by electro-catalytic reactor. Relative to that of pristine TiO, the intense lattice distortion on the (001) plane, an average lattice expansion of 2% on the (100) plane, and decrease of second shell peak of X-ray absorption spectra serve as compelling evidence for the formation of metal interstitials in HE-TiO.
View Article and Find Full Text PDFACS Omega
December 2024
Department of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
We herein report a microwave-assisted Buchwald-Hartwig double amination reaction to synthesize potential thermally activated delayed fluorescence compounds, forming C(sp)-N bonds between donor and acceptor units. Our approach reduces reaction times from 24 h to 10-30 min and achieves moderate to excellent yields, outperforming conventional heating methods. The method is compatible with various aryl bromides and secondary amines, including phenoxazine, phenothiazine, acridine, and carbazole.
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