Two unprecedented aconitine-type C19-diterpenoid alkaloids, refractines A-B (-), along with 12 known compounds (-) were isolated from the roots of (Finet et Gagnep.) Hand. -Mazz. Their structures were elucidated based on extensive spectroscopic analyses, including 1D and 2D NMR, IR, and HR-ESI-MS data. All compounds were tested for inhibitory activities against NO production in LPS induced RAW 264.7 macrophages, compounds and had slight inhibited NO production with rate of 29.4% and 22.1% at the concentration of 30 μM, respectively.
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| http://dx.doi.org/10.1080/14786419.2023.2223736 | DOI Listing |
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Four new C-diterpenoid alkaloids from .
J Asian Nat Prod Res
July 2019
a School of Life Science and Engineering , Southwest Jiaotong University, Chengdu 610031 , China.
Four new C-diterpenoid alkaloids, rotundifosines D-G (), along with eight known ones () were isolated from the whole plant of Kar. & Kir. The structures of the compounds were elucidated on the basis of spectroscopic analyses, including HR-ESI-MS and 1D, 2D NMR.
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