The hormone-like protein irisin is involved in browning of adipose tissue and regulation of metabolism. Recently, Mu et al. identified the extracellular chaperone heat shock protein-90 (Hsp90) as the activating factor for "opening" αVβ5 integrin receptor, allowing for high-affinity irisin binding and effective signal transduction.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593114 | PMC |
| http://dx.doi.org/10.1016/j.cmet.2023.06.002 | DOI Listing |
Publication Analysis
Top Keywords
extracellular hsp90
4
hsp90 warms
4
warms integrins
4
integrins irisin
4
irisin workout
4
workout hormone-like
4
hormone-like protein
4
protein irisin
4
irisin involved
4
involved browning
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!