AI Article Synopsis

  • The guidelines aim to update the 2017 clinical practice guideline (CPG) from the European Society of Intensive Care Medicine (ESICM), focusing on adult patients with acute respiratory distress syndrome (ARDS), including cases related to COVID-19.
  • An international panel of clinical experts collaborated to create these guidelines, using established methods like the PRISMA statement for systematic reviews and the GRADE approach for assessing evidence quality and making recommendations.
  • The CPG responds to 21 specific questions and offers recommendations across several areas, such as respiratory support strategies (like high-flow nasal cannula and non-invasive ventilation) and includes expert opinions on clinical practices and future research directions.

Article Abstract

The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients' representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical practice and identifies the areas of future research.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354163PMC
http://dx.doi.org/10.1007/s00134-023-07050-7DOI Listing

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