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Impact of coronary artery tortuosity on outcomes following stenting with newer-generation drug-eluting stents. An analysis of the randomized BIOFLOW trials.
Rev Esp Cardiol (Engl Ed)
January 2025
Department of Cardiology, Internal Medicine II, Medical University of Vienna, Vienna, Austria. Electronic address:
Introduction And Objectives: Patients undergoing percutaneous coronary intervention in vessels with moderate-to-severe tortuosity are at higher risk of adverse outcomes, but data are scarce in the era of newer-generation stents. We compared outcomes following percutaneous coronary intervention in vessels with moderate-to-severe tortuosity using a bioresorbable-polymer sirolimus-eluting stent (BP-SES) vs a durable-polymer everolimus-eluting stent.
Methods: A total of 2350 patients from the BIOFLOW II, IV, and V randomized trials were stratified into 2 groups based on target-vessel tortuosity: none-to-mild and moderate-to-severe.
Enhancing percutaneous coronary intervention using TriVOCTNet: a multi-task deep learning model for comprehensive intravascular optical coherence tomography analysis.
Phys Eng Sci Med
January 2025
Faculty of Engineering, Department of Biomedical Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Article Synopsis
- Neointimal coverage and stent apposition are critical for improving percutaneous coronary interventions (PCI), but current algorithms struggle with automating the analysis of diverse stent types and preselecting necessary segments.
- This study introduces TriVOCTNet, a multi-task deep learning model designed to automate the classification, lumen segmentation, and stent strut segmentation in IVOCT images, all within one efficient network.
- TriVOCTNet demonstrated impressive accuracy with high classification rates and precise segmentation outputs, indicating its potential for enhancing clinical practices in PCI procedures.
Evaluation of the interface of metallic-coated biodegradable polymeric stents with prokaryotic and eukaryotic cells.
Bioact Mater
April 2025
University of Coimbra, CEMMPRE, Department of Mechanical Engineering, 3030-788, Coimbra, Portugal.
Polymeric coronary stents, like the ABSORB™, are commonly used to treat atherosclerosis due to their bioresorbable and cell-compatible polymer structure. However, they face challenges such as high strut thickness, high elastic recoil, and lack of radiopacity. This study aims to address these limitations by modifying degradable stents produced by additive manufacturing with poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) with degradable metallic coatings, specifically zinc (Zn) and magnesium (Mg), deposited via radiofrequency (rf) magnetron sputtering.
View Article and Find Full Text PDFLong-Term Outcomes of True Versus Nontrue Coronary Bifurcation Lesions Treated With Bioresorbable Polymer Sirolimus-Eluting Ultimaster Stent Under Intravascular Imaging Guidance.
Am J Cardiol
December 2024
Department of Cardiovascular Medicine, Sapporo Cardiovascular Clinic, Sapporo Heart Center, Sapporo, Japan.
Limited evidence exists regarding the long-term outcomes of true versus nontrue coronary bifurcation lesions (CBLs) treated with current-generation drug-eluting stents and intravascular imaging guidance. The Sapporo Cardiovascular Clinic (SCVC) registry was a prospective, single-center, all-comers registry enrolling 1,727 consecutive patients treated with bioresorbable polymer sirolimus-eluting stent under complete imaging guidance. From this registry, 440 patients with CBLs (25.
View Article and Find Full Text PDFDevice-related patient outcomes for coronary stents: A MAUDE database analysis.
Heliyon
December 2024
Harvard University, Cambridge, MA, United States.
The growing prevalence of coronary artery diseases in the US corresponds to the increasing use of minimally invasive techniques that require coronary stents. Although extensive research is available on the perioperative outcomes of the 3 stent options - bare-metal stents (BMS), drug-eluting stents (DES), and bioresorbable drug-eluting stents (BVS), a knowledge gap exists in the longitudinal monitoring of patient outcomes due to device-related causes. Therefore, our study examines the device-related patient outcome and the relative performance for BMS, DES, and BVS.
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