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IL-5, CCL2, and CXCL8 in sinus mucous are higher in patients with AERD relative to aspirin-tolerant patients with CRS These mediators are pleiotropic, leading to widescale inflammatory processes contributing to AERD AERD is not only a T2 disease but heterogeneous: this may explain the refractory nature of AERD.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11660759 | PMC |
| http://dx.doi.org/10.1002/alr.23216 | DOI Listing |
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Article Synopsis
- Research explored the effectiveness of hydrogen-rich saline (HRS) for nasal irrigation after chronic rhinosinusitis (CRS) surgery, which is a commonly challenging long-term treatment.
- A study with 61 patients compared HRS to regular saline (NS) post-surgery, measuring outcomes through various scoring methods over 12 weeks.
- Results showed that the HRS group had better outcomes in reducing discomfort and achieving clinical cure compared to the NS group, without significant side effects.
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